Nasal-type NK/T-cell lymphoma: a case report.

Acta Dermatovenerol Alp Pannonica Adriat

Nis Clinical Centre, Clinic of Dermatovenereology, Bul. Z. Djindjića 48, 18 000 Nis, Serbia.

Published: June 2007

AI Article Synopsis

  • Extranodal NK/T-cell lymphoma is a rare type of lymphoma, representing less than 1% of all cases, with higher prevalence noted in Asia and South America.
  • A 67-year-old woman presented with painful, reddish-blue nodules on her scalp, which were biopsied and revealed atypical lymphoid cells showing an angiocentric growth pattern.
  • The immunophenotype tests indicated the presence of specific markers (CD45RO +, CD56 +, CD3 +, CD20 -), confirming the diagnosis of NK/T-cell lymphoma, though optimal treatment options remain unclear.

Article Abstract

Extranodal NK/T-cell lymphoma represents less than 1% of all lymphomas, but is more common in Asia and South America. We present a 67-year-old female with a 10-month history of four reddish-blue firm and painful nodules in the parietal region of the head, ranging in size from 1 to 5 cm. Two nodules were taken for biopsy, which showed atypical lymphoid cells with angiocentric growth pattern. The immunophenotype of the tumor cells was CD45RO +, CD56 +, CD3 + (epsilon chain), CD20-, consistent with the diagnosis of NK/T-cell lymphoma. NK/T-cell lymphomas are rare and the optimal treatment has not been clearly established.

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