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Nanoparticle-assisted PCR: fundamentals, mechanisms, and forensic implications.
Int J Legal Med
January 2025
Biological and Life Sciences, School of Arts and Sciences, Ahmedabad University, Central Campus, Navrangpura, Ahmedabad, Gujarat, India.
Polymerase Chain Reaction (PCR) has transformed forensic DNA analysis but is still limited when dealing with compromised trace or inhibitor-containing samples. Nanotechnology has been integrated into nanoPCR (nanoparticle-assisted PCR) to overcome these obstacles. Nanomaterials improve PCR sensitivity, selectivity, and efficiency.
View Article and Find Full Text PDFReconsidering the Relationship Between Criminal Insanity and Delusions.
J Am Acad Psychiatry Law
January 2025
Dr. Gröning is a Professor, Faculty of Law, University of Bergen, Norway and a Senior Researcher, Regional Centre for Research and Education in Forensic Psychiatry and Psychology, Haukeland University Hospital, Bergen, Norway. Dr. Radovic is an Associate Professor, Department of Philosophy, Linguistics and Theory of Science and Centre for Ethics, Law and Mental Health, University of Gothenburg, Gothenburg, Sweden. Dr. Haukvik, is a Professor, Department of Mental Health and Addiction, Institute for Clinical Medicine, University of Oslo, Norway and Senior Researcher, Regional Centre for Research and Education in Forensic Psychiatry and Psychology, Oslo University Hospital, Oslo, Norway.
This article discusses the relevance of delusions for a finding of criminal insanity. The authors start from the recognition that the psychiatric notion of delusion is considered relevant to criminal insanity in most jurisdictions and therefore integrates psychiatric perspectives to define delusions. The key focus is on the differences regarding how and why delusions matter legally between the Anglo-American and the Norwegian approach to criminal insanity.
View Article and Find Full Text PDFNational Consensus on the Assessment of Visual Function for Driving in Switzerland.
Klin Monbl Augenheilkd
January 2025
Department of Ophthalmology, University Hospital Zurich, University of Zurich, Zurich, Switzerland.
Purpose: To establish a national consensus on assessing visual function for fitness to drive in Switzerland.
Methods: The minimum medical requirements for visual function for fitness to drive are regulated by Swiss Federal Law, namely, by the Traffic Licensing Ordinance (TLO). The medical examination techniques relevant in this context and their assessment are not further specified therein, which leads to legal inequality among drivers and uncertainty among examiners.
Clinical and imaging aspects associated with persistent apical periodontitis: subsides for the treatment decision-making process.
Clin Oral Investig
January 2025
Department of Restorative Dentistry, School of Dentistry of Ribeirão Preto, University of São Paulo (USP), Ribeirão Preto, SP, Brazil.
Objectives: To evaluate cases of persistent apical periodontitis (PAP) and what are the imaging and clinical aspects that could be considered in the PAP diagnosis and in their treatment decision-making process.
Methodology: 423 patients with apical periodontitis at the time of non-surgical root canal treatment (NSRCT) were followed-up for at least 1 year. Periapical radiographic images were used to compare and determine periapical status at each time using the PAI scoring system.
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