Psoriatic arthritis (PA) occurs in about 30% of patients with psoriasis. Although polyneuropathy is described in association with many connective tissue diseases, it is rarely reported in the autoimmune dermatoses. We describe 3 patients with polyneuropathy associated with PA. The clinical and electrophysiologic features are consistent with a chronic distal symmetric sensorimotor axonal process. PA-associated neuropathy should be considered in the differential diagnosis of chronic length-dependent axonal polyneuropathies.

Download full-text PDF

Source
http://dx.doi.org/10.1097/CND.0b013e31814839d6DOI Listing

Publication Analysis

Top Keywords

psoriatic arthritis-associated
4
arthritis-associated polyneuropathy
4
polyneuropathy report
4
report three
4
three cases
4
cases psoriatic
4
psoriatic arthritis
4
arthritis occurs
4
occurs 30%
4
30% patients
4

Similar Publications

Article Synopsis
  • * These conditions share common features like the absence of autoantibodies and genetic links, along with symptoms affecting joints and other body areas, but their exact causes are still not fully understood.
  • * The article reviews current knowledge about the mechanisms behind ankylosing spondylitis, including genetic factors, environmental triggers, and immune responses that lead to inflammation and joint issues.
View Article and Find Full Text PDF

Objective: Psoriatic arthritis (PsA) is an inflammatory arthritis associated with psoriasis. Adding to studies focused on the role of T cells and macrophages, we sought to investigate the systemic activation of leukocytes in PsA.

Methods: We assessed the activation state of leukocyte populations, including polymorphonuclear neutrophils (PMNs) and monocyte/macrophages, in blood and synovial fluid (SF) by multicolour flow cytometry.

View Article and Find Full Text PDF

Treatment strategies for Spondyloarthritis: Implementation of precision medicine - Or "one size fits all" concept?

Autoimmun Rev

October 2024

Department of Gastroenterology, Infectiology and Rheumatology (including Nutrition Medicine), Charité - Universitätsmedizin Berlin, Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany; Epidemiology unit, German Rheumatism Research Centre, Berlin, Germany; Division of Rheumatology, Department of Medicine, University Health Network and University of Toronto, Toronto, Canada.

Spondyloarthritis (SpA) is a term to describe a group of chronic inflammatory rheumatic diseases, which have common pathophysiological, genetic, and clinical features. Under the umbrella term SpA, two main groups are subsumed: axial SpA (radiographic axSpA and non-radiographic axSpA) and peripheral SpA (with the leading representative being psoriatic arthritis (PsA) but also arthritis associated with inflammatory bowel disease (IBD), reactive arthritis, and undifferentiated pSpA). The key clinical symptom in axSpA is chronic back pain, typically with inflammatory characteristics, which starts in early adulthood, while the leading clinical manifestations of peripheral SpA (pSpA) are arthritis, enthesitis, and/or dactylitis.

View Article and Find Full Text PDF
Article Synopsis
  • - Psoriatic arthritis (PsA) is a chronic inflammatory arthritis closely linked with psoriasis (PsO), and this study aims to detect asymptomatic PsA using ultrasound (US) exams while exploring different stages of PsO.
  • - Over a study period from September 2020 to January 2022, 547 patients with moderate-to-severe PsO were examined, revealing that 114 were diagnosed with PsA, with 16.45% exhibiting subclinical forms of the disease.
  • - The study found that ultrasound could effectively identify abnormalities, showing a high sensitivity and specificity, particularly in areas such as the interphalangeal joint, knee joint, and calcaneal tendon, which are key indicators for early detection of
View Article and Find Full Text PDF

Psoriatic arthritis (PsA) is a chronic inflammatory arthritis associated with psoriasis. The use of inflammatory markers can be disappointing in PsA since they are elevated in only about half of the patients. This study aimed to measure serum calprotectin level in PsA patients and to assess its association with disease activity in PsA (DAPSA) and musculoskeletal ultrasound findings.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!