AI Article Synopsis
- Locomotion in mammals is primarily regulated by intrinsic spinal cord networks known as central pattern generators (CPGs).
- The functionality of these CPGs relies on the balance between inhibitory and excitatory neurons.
- Recent research highlights the importance of excitatory synaptic transmission in these networks, particularly how specific excitatory neurons coordinate muscle activity and produce rhythmic movements.
Article Abstract
Locomotion in mammals is to a large degree controlled directly by intrinsic spinal networks, called central pattern generators (CPGs). The overall function of these networks is governed by interaction between inhibitory and excitatory neurons. In the present review, we will discuss recent findings addressing the role of excitatory synaptic transmission for network function including the role of specific excitatory neuronal populations in coordinating muscle activity and in generating rhythmic activity.
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| http://dx.doi.org/10.1016/j.brainresrev.2007.07.002 | DOI Listing |
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