The sensitivity and specificity of a new clinical sign of hypocalcaemia were evaluated. The Swan-neck sign, wherein infants with symptomatic hypocalcaemia keep their big toe hyperextended at the metatarsophalangeal joint and flexed at the interphalangeal joint, was looked for in 25 infants presenting with non-febrile seizures, alongside their serum calcium levels. The study showed that the sign had a sensitivity of 63.6% and specificity of 66.6%. (Predictive values of positive and negative tests were 93.3% and 20%, respectively.) This is compared with the standard Trousseau and Chvostek signs.
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http://dx.doi.org/10.1258/004947507782333008 | DOI Listing |
J Med Case Rep
August 2024
Department of Dermatology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.
Background: Dermatofibromas, also known as benign fibrous histiocytomas, are among the most common cutaneous soft-tissue lesions. Association of multiple dermatofibromas with some diseases was described and it has not been reported with Ehlers-Danlos syndrome before. We present a case with Ehlers-Danlos syndrome and multiple dermatofibromas.
View Article and Find Full Text PDFCan J Kidney Health Dis
November 2021
Department of Medicine, Dalhousie University, Halifax, NS, Canada.
Rationale: Primary hyperoxaluria (PH) is a rare autosomal recessive disorder more commonly diagnosed in children or adolescents. Owing to its rarity and heterogeneous phenotype, it is often underrecognized, resulting in delayed diagnosis, including diagnosis after end-stage kidney disease (ESKD) has occurred or recurrence after kidney-only transplantation.
Case Presentation: A 40-year-old Caucasian Canadian woman with a history of recurrent nephrolithiasis since age 19 presented with ESKD and cutaneous symptoms.
Scurvy results from a deficiency of vitamin C, a nutrient otherwise known as ascorbic acid. Today, scurvy is rare yet emerges in select patients. The patient reported herein developed scurvy secondary to deliberate avoidance of vitamin C-rich foods.
View Article and Find Full Text PDFRheumatology (Oxford)
November 2009
Department of Rheumatology, Lund University Hospital, S-22185 Lund, Sweden.
Objectives: The aim of this study was to investigate the occurrence and significance of hand deformities during the first 10 years of RA.
Methods: One hundred and eighty-three early RA patients were included in the study during 1985-89. Mean +/- S.
Trop Doct
October 2007
Department of Pediatrics, St Stephens Hospital, Tis Hazari, Delhi 110054, India.
The sensitivity and specificity of a new clinical sign of hypocalcaemia were evaluated. The Swan-neck sign, wherein infants with symptomatic hypocalcaemia keep their big toe hyperextended at the metatarsophalangeal joint and flexed at the interphalangeal joint, was looked for in 25 infants presenting with non-febrile seizures, alongside their serum calcium levels. The study showed that the sign had a sensitivity of 63.
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