Background And Objectives: Family medicine residents encounter and treat a significant number of skin diseases. It is important for them to make correct diagnostic and treatment decisions for these diseases. Our study was done to assess residents' competence in diagnosing and treating skin disorders before and after a brief educational intervention.
Methods: A questionnaire containing photographs of 40 skin conditions was administered to 45 family medicine residents, who were asked to identify the conditions shown in the photos. The subsequent intervention consisted of a lecture by a senior resident and a photographic quick reference guide, which was given to each resident. A posttest was administered 8 months later to again assess residents' ability to identify skin conditions. For comparisons of pretest and posttest performance, t tests were used.
Results: Participants showed significant improvement in both diagnosing (from 22.3% correct to 54.9% correct) and providing treatment recommendations (from 15.4% correct to 48.5% correct) for skin disorders.
Conclusions: A peer-prepared lecture combined with a take-home photographic quick reference guide is an effective way to improve a family medicine resident's knowledge of skin disorders.
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Front Biosci (Landmark Ed)
November 2024
Department of General Surgery, The First Affiliated Hospital of Anhui Medical University, 230022 Hefei, Anhui, China.
Background: Gallstone formation is a common digestive ailment, with unclear mechanisms underlying its development. Dysfunction of the gallbladder smooth muscle (GSM) may play a crucial role, particularly with a high-fat diet (HFD). This study aimed to investigate the effects of an HFD on GSM and assess how it alters contractility through changes in the extracellular matrix (ECM).
View Article and Find Full Text PDFJ Integr Neurosci
December 2024
Laboratory of Genomic Research, Research Institute for Genetic and Molecular Epidemiology, Kursk State Medical University, 305041 Kursk, Russia.
Background: Heat shock proteins (HSPs) play a critical role in the molecular mechanisms of ischemic stroke (IS). A possible role for HSP40 family proteins in atherosclerosis progression has already been revealed; however, to date, molecular genetic studies on the involvement of genes encoding proteins of the HSP40 family in IS have not yet been carried out.
Aim: We sought to determine whether nine single nucleotide polymorphisms (SNPs) in genes encoding HSP40 family proteins (, , , , and ) are associated with the risk and clinical features of IS.
Biochem Res Int
December 2024
Kentucky College of Osteopathic Medicine, University of Pikeville, Pikeville 41501, Kentucky, USA.
Alzheimer's disease (AD), a neurological disorder, is one of the major reasons for memory loss in the world. AD is characterized by a sequela of cognitive and functional decline caused by brain cell degeneration. Paeoniflorin is a monoterpenoid glycoside found in plants of the Paeoniaceae family, which are known for their medicinal properties including dementia.
View Article and Find Full Text PDFChem Biomed Imaging
December 2024
Shu Chien-Gene Lay Department of Bioengineering, University of California San Diego, La Jolla, California 92093, United States.
Nanoscale surface topography is an effective approach in modulating cell-material interactions, significantly impacting cellular and nuclear morphologies, as well as their functionality. However, the adaptive changes in cellular metabolism induced by the mechanical and geometrical microenvironment of the nanotopography remain poorly understood. In this study, we investigated the metabolic activities in cells cultured on engineered nanopillar substrates by using a label-free multimodal optical imaging platform.
View Article and Find Full Text PDFJ West Afr Coll Surg
August 2024
College of Medicine, University of Ibadan, Oyo State, Nigeria.
Background: As the field of surgery continues to evolve, subspecialty training is fast becoming integral to surgical education. Presently, orthopaedic surgery residents have opportunities to subspecialise in different areas.
Objectives: The aim of this study was to determine the factors affecting the choice of desired subspecialties amongst orthopaedic surgery residents in southern Nigeria.
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