The goal of numeric analysis of aortic blood flow is to evaluate the mechanisms leading to an aortic aneurysm with regard to the risk of a rupture and to describe the effect of interventional therapy. Numeric analysis is based on virtual models of vascular structures and the physical characteristics of the vessel wall, of blood as fluidum, and the blood flow. Using this information, numeric analysis solves the appropriate equations. The results can be displayed quantitatively and qualitatively. The results of numeric flow simulation show that in abdominal aortic aneurysms the wall pressure, which is of vital importance for the risk of rupture, depends on several factors, one being the location of the intraluminal thrombus. In models of aneurysms after stent grafting, numeric analysis can be used to evaluate factors leading to stent migration. Although numeric analysis of aortic blood flow still has several limitations, recent studies have shown that this method has the potential for improved estimation of the rupture risk of aortic aneurysms in the near future.
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http://dx.doi.org/10.1007/s00117-007-1576-7 | DOI Listing |
JAMA Netw Open
January 2025
Department of Nutritional Sciences, University of Toronto, Toronto, Ontario, Canada.
Importance: Ultraprocessed foods (UPF), characterized as shelf-stable but nutritionally imbalanced foods, pose a public health crisis worldwide. In adults, UPF consumption is associated with increased obesity risk, but findings among children are inconsistent.
Objectives: To examine the associations among UPF intake, anthropometric adiposity indicators, and obesity status in Canadian children.
BJOG
January 2025
Obstetrics and Gynaecology Department, Ain Shams University, Cairo, Egypt.
Background: Artificial oocyte activation (AOA) is used to improve fertilisation rates in intracytoplasmic sperm injection (ICSI) cycles.
Objectives: To assess the effectiveness of AOA on fertilisation, embryo development, and clinical outcomes, including live birth.
Search Strategy: We searched PubMed, Cochrane, and Scopus from January 1990 to March 2024 using terms related to 'artificial oocyte activation' and 'ICSI.
Pharmacoepidemiol Drug Saf
February 2025
Netherlands Pharmacovigilance Centre Lareb, 's Hertogenbosch, Hertogenbosch, the Netherlands.
Background: Vitamin B6 deficiency is linked to neurological disorders. However, supplementation with high doses of vitamin B6 has also been linked to neuropathy as an adverse drug reaction. Review of cases from the Dutch Spontaneous Reporting System (SRS) and other data led to a regulatory action to lower the maximum daily dose (DD) of vitamin B6 in supplements to 21 mg/day from October 1, 2018.
View Article and Find Full Text PDFMed Phys
January 2025
National Institute for Mathematical Sciences, Daejeon, Republic of Korea.
Background: In X-ray computed tomography (CT), metal-induced beam hardening artifacts arise from the complex interactions between polychromatic X-ray beams and metallic objects, leading to degraded image quality and impeding accurate diagnosis. A previously proposed metal-induced beam hardening correction (MBHC) method provides a theoretical framework for addressing nonlinear artifacts through mathematical analysis, with its effectiveness demonstrated by numerical simulations and phantom experiments. However, in practical applications, this method relies on precise segmentation of highly attenuating materials and parameter estimations, which limit its ability to fully correct artifacts caused by the intricate interactions between metals and other dense materials, such as bone or teeth.
View Article and Find Full Text PDFNurs Health Sci
March 2025
College of Nursing and Allied Health Sciences, St. Paul University Manila, Metro Manila, Philippines.
This study uses network meta-analysis to evaluate the relative effectiveness of different interventions (behavioral, psychological, and comprehensive) in alleviating compassion fatigue, burnout, and secondary traumatic stress, as well as in improving compassion satisfaction among nurses, aiming to provide evidence-based insights for enhancing nurses' mental health and care quality. Compassion fatigue in nurses negatively affects their mental health, patient care quality, and healthcare efficiency. Various interventions (psychological, behavioral, and integrated) target this issue, but evidence on their effectiveness is inconclusive.
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