Nisin-triggered activity of Lys44, the secreted endolysin from Oenococcus oeni phage fOg44.

J Bacteriol

Instituto de Ciência Aplicada e Tecnologia da Faculdade de Ciências da Universidade de Lisboa, 1749-016 Lisboa, Portugal.

Published: January 2008

The intrinsic resistance of Oenococcus oeni cells to the secreted endolysin from oenophage fOg44 (Lys44) was investigated. Experiments with several antimicrobials support the hypothesis that the full activity of Lys44 requires sudden ion-nonspecific dissipation of the proton motive force, an event undertaken by the fOg44 holin in the phage infection context.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2223723PMC
http://dx.doi.org/10.1128/JB.01195-07DOI Listing

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