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Effects of enteral insulin on enteral diet tolerance in premature infants: systematic review.
Rev Paul Pediatr
January 2025
Fundação Lusíada, Faculdade de Ciências Médicas de Santos, Santos, SP, Brazil.
Objective: The primary objective of this systematic review was to evaluate the effect of enteral insulin supplementation provided to premature newborns on the time to achieve full enteral feeding. Secondary objectives included evaluating the effects on weight gain, the occurrence of adverse events, and mortality.
Data Source: A systematic review of randomized clinical trials was conducted using the databases PubMed, Scientific Electronic Library Online (SciELO), clinicaltrials.
The impact of a tailored nutrition intervention delivered for the duration of hospitalisation on daily energy delivery for patients with critical illness (INTENT): a phase II randomised controlled trial.
Crit Care
January 2025
Australian and New Zealand Intensive Care Research Centre, School of Public Health and Preventive Medicine, Department of Epidemiology and Preventative Medicine, Monash University, 553 St Kilda Road, Melbourne, VIC, Australia.
Background: Nutrition interventions commenced in ICU and continued through to hospital discharge have not been definitively tested in critical care to date. To commence a program of research, we aimed to determine if a tailored nutrition intervention delivered for the duration of hospitalisation delivers more energy than usual care to patients initially admitted to the Intensive Care Unit (ICU).
Methods: A multicentre, unblinded, parallel-group, phase II trial was conducted in twenty-two hospitals in Australia and New Zealand.
Inpatient Nutritional Considerations in Inflammatory Bowel Disease.
Curr Gastroenterol Rep
December 2025
St Luke's University Hospital, Fountain Hill, USA.
Article Synopsis
- This review focuses on understanding malnutrition in hospitalized patients with inflammatory bowel disease (IBD), detailing its causes, diagnosis, and treatment for both adults and children.
- Up to 85% of IBD patients experience malnutrition, leading to more health complications, longer hospital stays, and higher mortality rates.
- Early detection using tools like Subjective Global Assessment and implementing nutritional interventions such as exclusive enteral nutrition and parenteral nutrition can significantly enhance patient recovery and outcomes, necessitating further research to standardize nutritional care.
Efficacy and Safety of a Combination of Enteral and Parenteral Nutrition Support in the Postoperative Period for Patients with Gastrointestinal Cancer: A Systematic Review and Meta-Analysis.
Balkan Med J
January 2025
Department of Gastrointestinal Surgery, Changzhou Maternal and Child Health Care Hospital, Changzhou, China.
Article Synopsis
- Postoperative nutritional support is crucial for improving recovery and outcomes in patients with gastrointestinal cancer, with enteral and parenteral nutrition being key strategies.
- A meta-analysis of 11 randomized controlled trials found that combining enteral nutrition (EN) with parenteral nutrition (PN) significantly enhances recovery, nutritional function, and immune response compared to using either method alone.
- The study also revealed that the EN-only group had a higher risk of postoperative complications, such as nausea, vomiting, and diarrhea, indicating that combined nutrition may have better overall safety and efficacy.
Forty-seventh ASPEN Presidential Address: Parenteral nutrition compounding-Advancement or regression, where do we stand?
JPEN J Parenter Enteral Nutr
January 2025
Department of Pharmacy, Mississippi Baptist Medical Center, Jackson, Mississippi, USA.
Parenteral nutrition (PN), a high-alert medication, is an important lifesaving modality. The American Society for Parenteral and Enteral Nutrition (ASPEN) has historically provided guidelines and recommendations for the safe and efficacious use of PN. These recommendations have included detailed guidance regarding the compounding of this highly complex medication.
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