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The relationship between cannabis use and mental health is complex, as studies often report seemingly contradictory findings regarding whether cannabis use results in more positive or negative treatment outcomes. With an increasing number of individuals using cannabis for both recreational (i.e.

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Cannabinoids for treating psychiatric disorders in youth: a systematic review of randomized controlled trials.

Child Adolesc Psychiatry Ment Health

December 2024

University Hospital of Child and Adolescent Psychiatry and Psychotherapy, University of Bern, Bern, Switzerland.

Article Synopsis
  • The systematic review investigates the effectiveness of cannabinoids for treating psychiatric disorders in individuals aged 0-25, synthesizing data from randomized placebo-controlled trials.
  • The analysis included 8 clinical trials with 474 participants, revealing a modest overall positive effect for symptom improvement, particularly in studies focusing on autism spectrum disorder.
  • Adult participants exhibited greater effects from cannabinoid treatment compared to younger populations, with both whole plant and pharmaceutical preparations showing similar efficacy.
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High Prescribing: A Case Study of High-Potency Medicinal Cannabis Inducing Psychosis.

Case Rep Psychiatry

December 2024

Turning Point Drug and Alcohol Service, Eastern Health, Box Hill, Victoria, Australia.

There has been a recent significant increase in medical cannabis prescribing in Australia despite weak evidence for its effectiveness in treating the most common indications. Concern has been raised about the potential harms of inappropriate prescription of cannabis; however, there have been no prior published cases of psychosis secondary to medicinal cannabis in Australia. We present a case of a 21-year-old Indigenous male with psychosis following switching from illicitly obtained cannabis to prescription cannabis, which resulted in Othello delusions towards his partner, violence towards her and ultimately an attempt to end his life.

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Background: Substance use may be associated with the onset of psychotic symptoms, necessitating treatment for individuals with comorbid mental health and substance use disorders (MHD/SUD). COVID-19 significantly impacted individuals with MHD/SUD, reducing access to appropriate care and treatment. Changes in drug availability and prices during the pandemic may have influenced drug consumption.

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Psychedelic use and bipolar disorder - An investigation of recreational use and its impact on mental health.

J Affect Disord

December 2024

Louis A. Faillace Department of Psychiatry & Behavioral Sciences, University of Texas Health Science Center at Houston, 1941 East Rd, Houston, TX 77054, USA. Electronic address:

Psychedelic substances such as psilocybin have recently gained attention for their potential therapeutic benefits in treating depression and other mental health problems. However, individuals with bipolar disorder (BD) have been excluded from most clinical trials due to concerns about manic switches or psychosis. This study aimed to systematically examine the effects of recreational psychedelic use in individuals with BD.

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