AI Article Synopsis
Article Abstract
Environmental toxicants comprise a number of man-made organic chemicals which may resist metabolism or their metabolites may persist in the environment and accumulate in the food chain. Some of these persistent chemicals are carried over long distances via the atmospheric transport and can have biological effects in fish, wildlife and humans. In this review the relationship between structure of these chemicals, their mode of action and their possible roles in adverse developmental and reproductive processes in humans will be discussed. The focus will be on model polychlorinated biphenyls and dioxins, organochlorines, phthalates, a constituent of cigarette smoke (benzo-a-pyrene), synthetic polymers (polybrominated diphenyl ethers and polyfluorinated compounds), and a fungicide (vinclozolin).
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.2174/138161207782110499 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Regulation of anaplerotic enzymes by melatonin enhances resilience to cadmium toxicity in Vigna radiata (L.) R. Wilczek.
Plant Physiol Biochem
January 2025
Department of Botany and Microbiology, College of Science, King Saud University, Riyadh, 11451, Saudi Arabia.
Melatonin (Mel) is a tryptophan-derived (N-acetyl-5-methoxytryptamine) molecule. In the present study, role of Mel in the regulation of various anaplerotic enzymes is discussed in relation to N metabolism and H-ATPase activity in mung bean under Cd stress. The application of Mel to the Cd-stressed mung bean seedlings was remarkable in improving the activity of hexokinase (35.
View Article and Find Full Text PDFTrace elements in fish species from the Punjnad headworks: Bioaccumulation and human health risk assessment.
PLoS One
January 2025
Department of Entomology, Faculty of Agriculture and Environment, The Islamia University of Bahawalpur, Bahawalpur, Pakistan.
Aquatic toxicology, as a result of industrial and agrieqcultural effluences, has become a global concern impacting not only the well-being of aquatic organisms but human health as well. The current study evaluated the impact of four toxic trace elements (TTEs) Cadmium (Cd), copper (Cu), lead (Pb), and nickel (Ni) in three organs (liver, gills, and muscles) of five fish species viz, Rita rita, Sperata sarwari, Wallago attu, Mastacembelus armatus, and Cirrhinus mrigala collected from right and left banks of Punjnad headworks during winter, spring, and summer. We investigated the accumulation (mg/kg) of these TTEs in fish in addition to the human health risk assessment.
View Article and Find Full Text PDFChemopreventive role of β-caryophyllene in DMBA-induced skin cancer: Modulation of apoptotic pathways and PI3K/Akt signaling in Swiss albino mice.
Adv Clin Exp Med
January 2025
Department of Dermatology, The Affiliated Hospital to Changchun University of Chinese Medicine, China.
Background: The skin, with its robust structural integrity and advanced immune defense system, serves as a critical protective barrier against environmental toxins and carcinogenic compounds. Despite this, it remains vulnerable to the harmful effects of certain hazardous agents.
Objectives: This study aimed to investigate the chemopreventive potential of β-caryophyllene (BCP) in mitigating 7,12-dimethylbenz[a]anthracene (DMBA)-induced skin carcinogenesis, focusing on the modulation of apoptosis and PI3K/AKT signaling pathways.
Rapid and Environment-Friendly LC-MS/MS for Simultaneous Analysis of Amino Acids in Veterinary Medicine.
Vet Med Sci
January 2025
Animal Disease Diagnosis Division, Animal and Plant Quarantine Agency (APQA), Ministry of Agriculture, Food and Rural Affairs, Gimcheon-si, Republic of Korea.
Background: Amino acid supplements are crucial for animal health and productivity. Traditional analysis methods face limitations like complexity, long testing times and toxic reagents. Therefore, a more efficient and reliable method is needed.
View Article and Find Full Text PDFCurcumin: A Potential Detoxifier Against Chemical and Natural Toxicants.
Phytother Res
January 2025
Chemical and Energy Engineering, Faculty of Engineering, Universiti Teknologi Brunei, Bandar Seri Begawan, Brunei.
The human body gets exposed to a variety of toxins intentionally or unintentionally on a regular basis from sources such as air, water, food, and soil. Certain toxins can be synthetic, while some are biological. The toxins affect the various parts of the body by activating numerous pro-inflammatory markers, like oxidative stresses, that tend to disturb the normal function of the organs ultimately.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!