The model of Monod, Wyman, and Changeux generates two sets of parameters when applied to oxygen binding in hemoglobin.

Biochem Biophys Res Commun

The Laboratory of Biochemistry and Genetics, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD 20892, USA.

Published: December 2007

The model of Monod, Wyman and Changeux is applied to binding phenomena where the Mass Law and its expansion are employed. In this communication the model of Monod, Wyman and Changeux (MWC) is applied to analyze the oxygen binding reaction in hemoglobin. The symmetrical structure of the MWC model with its three parameters is such that two sets of these parameters, rather than one, fit experimental data for the binding of oxygen to hemoglobin.

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.bbrc.2007.10.078DOI Listing

Publication Analysis

Top Keywords

model monod
12
monod wyman
12
wyman changeux
12
sets parameters
8
oxygen binding
8
model
4
changeux generates
4
generates sets
4
parameters applied
4
applied oxygen
4

Similar Publications

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!