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Autism Spectrum and gastrointestinal health: Screening on the influence of environmental factors on gastrointestinal problems.
Autism Res
December 2024
Department of Microbiology, Institute of Biomedical Sciences (ICB-USP), University of São Paulo, São Paulo, SP, Brazil.
Autism spectrum disorder (ASD) is a complex neurodevelopmental condition that combines genetic and environmental factors. The human microbiota is colonized by permanent or transitory microorganisms, depending on the host and the external factors controlling their permanence. The composition of the gut microbiota (GM) in ASD individuals is notably different from that in controls, which may contribute to the clinical conditions observed in these individuals.
View Article and Find Full Text PDFSanta Claus, the Tooth Fairy, and purported lifetime nondrinkers: Ramifications for observational evidence about alcohol and health.
Alcohol Clin Exp Res (Hoboken)
January 2025
National Drug Research Institute, Curtin University, Perth, Western Australia, Australia.
Exploration of oral hygiene practices, oral health status, and related quality of life of individuals residing in the Rorya district of Tanzania, East Africa.
Front Oral Health
October 2024
College of Medicine, University of Cincinnati, Cincinnati, OH, United States.
Article Synopsis
- Oral health is essential for quality of life, and this research focuses on understanding oral health practices and beliefs in the Rorya district of Tanzania, identifying barriers to care.
- The study involved intraoral examinations and interviews with a sample of 139 participants, revealing that females had higher Decayed Missing and Filled Teeth (DMFT) and Oral Health-Related Quality of Life (OHRQoL) scores, while males showed higher periodontal issues.
- Findings indicate a need for improved oral health maintenance in the community, emphasizing that disparities in access to resources contribute to poor oral health outcomes.
Cultural diversity of traditions for the disposal of exfoliated teeth: Implications for researchers.
Community Dent Oral Epidemiol
April 2024
Psychiatric and Neurodevelopmental Genetics Unit, Center for Genomic Medicine, Massachusetts General Hospital, Boston, Massachusetts, USA.
Objectives: For decades, researchers in anthropology and archaeology have used teeth, including exfoliated primary teeth, as fossil records of people's physical life experiences. Recently, researchers in psychiatry, epidemiology, environmental health and other fields have recognized the potential for teeth to serve as biomarkers of other early-life experiences, including trauma exposure and other types of psychosocial stress, which are potent determinants of later mental and physical health problems. Despite the emerging appreciation and value of teeth as biospecimens, little is understood about cultural beliefs and practices surrounding exfoliated teeth.
View Article and Find Full Text PDFHelp Comes from Unexpected Places: How a Tiny Fairy and a Tropical Fish may help us Model Mucopolysaccharidoses.
Endocr Metab Immune Disord Drug Targets
November 2023
Research and Development Unit, Department of Human Genetics, INSA.
Introduction: When it comes to disease modeling, countless models are available for Lysosomal Storage Diseases (LSD). Historically, two major approaches are well-established: in vitro assessments are performed in patient fibroblasts, while in vivo pre-clinical studies are performed in mouse models. Still, both platforms have a series of drawbacks.
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