AI Article Synopsis

  • A study analyzed 60 patients with nodular goiter to compare cytology and scintigraphy results with pathohistology.
  • Patients underwent various tests, and were divided into groups based on whether their lesions were tumor-related or non-tumor-related.
  • Cytologic diagnosis matched pathohistological diagnosis in 85% of cases, with no statistically significant difference observed between the two diagnostic methods.

Article Abstract

We compared cytologic and scintigraphic findings with pathohistologic diagnosis in 60 patients (11 males and 49 females) with nodular goiter. In the preoperative period, apart from clinical examination, all patients underwet thyroid gland scyntigraphy, puncture, T3, T4, TSH hormon test, and if clinically relevant, thyroglobulin. On the basis of pathohistologic diagnosis, two groups were formed: nontumour and tumour lesions. The nontumour lesion gruop consisted of 24 colloid and 8 cystic noduli. Cytologic diagnosis was confirmed in 29 cases. All cystic and 6 colloid noduli were scintigraphically "cold", while the rest were "relatively cold". In the tumour lesion group there were 14 follicular and 3 Hürthle's adenomas, 5 papillary, 1 follicular, 3 anaplastic and 2 metastatic carcinomas. Cytologic diagnosis was confirmed in 22 cases. All noduli were "cold". Cytologic diagnosis was compatible with pathohistologic diagnosis in 85% of cases. The difference between cytologic and pathohistologic diagnosis was not statistically significant.

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