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Dementia Care Research and Psychosocial Factors.
Alzheimers Dement
December 2024
University of Southern California, Los Angeles, OH, USA.
Background: Family caregivers to persons living with dementia are at risk of financial strain from the high out-of-pocket costs of care and reduced employment opportunities. Financial strain disproportionately affects U.S.
View Article and Find Full Text PDFDementia Care Research and Psychosocial Factors.
Alzheimers Dement
December 2024
University of Alabama, Birmingham, AL, USA.
Background: Black/African Americans in the Deep South have been subjected to social segregation, discrimination, and other forms of systematic injustices that continue to negatively impact this population's social determinants of health (SDoH). Healthy People 2030 has outlined a framework describing how adverse SDoH are associated with health inequities including higher rates of Alzheimer's disease and related dementias (ADRD). Historically, it has been challenging to recruit citizens from this region to participate in brain aging-related research studies.
View Article and Find Full Text PDFInvestigations for Suspected Head and Neck Squamous Cell Carcinoma of Unknown Primary (HNSCCUP): A National Cohort Study.
Clin Otolaryngol
January 2025
Head and Neck Unit, The Royal Marsden Hospital, London, UK.
Objectives: Head and neck squamous cell carcinoma from unknown primary (HNSCCUP) is a rare and challenging condition. This study aimed to investigate the diagnostic pathways of suspected HNSCCUP patients in the United Kingdom.
Methods: A retrospective observational cohort study was conducted, over 5 years from January 2015, in UK Head and Neck centres of consecutive adults undergoing 18F-Fluorodeoxyglucose-PET-CT (PET-CT) within 3 months of diagnosis with metastatic cervical squamous cell carcinoma.
Functional significance of some common oxytocin receptor SNPs involved in complex human traits.
BMC Mol Cell Biol
January 2025
Faculty of Science, School of Psychology, University of Sydney, Sydney, NSW, Australia.
Background: Oxytocin function is associated with a range of human traits and is often indexed by common polymorphisms of the receptor gene OXTR. Little is known however about the functional significance of these polymorphisms.
Objectives: To examine the effects of common polymorphisms of OXTR on transcription expression in human neural cells.
Actinic keratosis with severe dysplasia and Bowen disease represent distinct pathways of intraepidermal squamous neoplasia: an immunohistochemical study.
Pathology
December 2024
Department of Anatomical Pathology, PathWest Laboratory Medicine, QEII Medical Centre, Perth, WA, Australia; School of Medicine, Notre Dame University, Fremantle, WA, Australia. Electronic address:
Intraepidermal squamous neoplasia is a precursor to invasive cutaneous squamous cell carcinoma. The most common type of intraepidermal squamous neoplasia is actinic keratosis (AK), although there is compelling clinicopathological evidence of a second distinct pattern of squamous dysplasia termed Bowen disease (BD). The distinction between these pathways of dysplasia has been inconsistently delineated in the literature.
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