Fraud and deceit in medical research is a serious issue that may be more prevalent than currently thought. This article examines the extent and history of medical research fraud and looks at the current and future mechanisms for detection and prevention.
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Background: Companies recently identified clinical study sites engaging in fraudulent practices, reducing success in Alzheimer's disease (AD) clinical trials. Successful trials are reliable despite possible victimization by these practices because these sites introduce a negative bias. Ease of simulating Alzheimer's diagnosis documentation (based on clinical or blood markers) and clinical outcome data, coupled with inadequate oversight by Contract Research Organizations (CROs), facilitates deceptive practices.
View Article and Find Full Text PDFBackground: Alzheimer's disease (AD) presents unique challenges in clinical trials involving small molecules. Multifaceted issues plague such trials, emphasizing susceptibility to fraud from clinical sites and "professional patients". The relative ease of simulating Alzheimer's diagnosis, coupled with inadequate oversight by Contract Research Organizations (CROs), creates fertile ground for deceptive practices.
View Article and Find Full Text PDFRecent advances on artificial intelligence-based approaches for food adulteration and fraud detection in the food industry: Challenges and opportunities.
Food Chem
December 2024
Nano-biotechnology and Translational Knowledge Laboratory, Department of Applied Biology, School of Biological Sciences, University of Science and Technology Meghalaya, Techno City, 9(th) Mile, Baridua, 793101, India; Centre for Herbal Pharmacology and Environmental Sustainability, Chettinad Hospital and Research Institute, Chettinad Academy of Research and Education, Kelambakkam 603103, India. Electronic address:
Food adulteration is the deceitful practice of misleading consumers about food to profit from it. The threat to public health and food quality or nutritional valuable make it a major issue. Food origin and adulteration should be considered to safeguard customers against fraud.
View Article and Find Full Text PDFHealth Care Fraud and Abuse: Lessons From One of the Largest Scandals of the 21st Century in the Field of Spine Surgery.
Ann Surg Open
June 2024
From the Division of Neurological Surgery, Saint Louis University School of Medicine, Saint Louis, MO.
Up to hundreds of billions of dollars are annually lost to fraud and abuse in the US health care, making it a significant burden on the system. This study investigates a specific instance of health care fraud in spine surgery, in which a medical device company ended up paying $75 million to settle violations of the False Claims Act. We review the surgical background regarding the kyphoplasty procedure, as well as its billing and reimbursement details.
View Article and Find Full Text PDFAnticounterfeiting and Fraud Mitigation Solutions for High-value Food Products.
J Food Prot
April 2024
Department of Agricultural, Forest and Food Sciences (DiSAFA) - Università degli Studi di Torino, Largo Paolo Braccini 2, 10095 Grugliasco (TO), Italy.
Globalization and the increasing complexity of supply chains have allowed food fraud to expand to a great extent. Some of the most serious effects of these deceitful activities are damage to a brand's reputation and trust, economic losses, and public health risks. The usual victims of food fraud are dairy, meat, fish, and seafood products, as well as fats/oils and alcoholic drinks.
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