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Molecular dynamics of three different α-helices in ribosomal protein L25 from .
Biochem Biophys Rep
December 2024
Institute of Protein Research, Russian Academy of Sciences, Pushchino, Moscow Region, Russia.
A true native protein state is realized in a water solution where proteins exhibit their dynamic properties important for the functioning. This is way we have analyzed the dynamics of α-helices inside ribosomal protein L25 from in a water solution. The dynamics of only main chain Cα-atoms have been simulated along the five independent trajectories at a total time 200ns.
View Article and Find Full Text PDFEffect of ginseng stem leaf extract on the production performance, meat quality, antioxidant status, immune function, and lipid metabolism of broilers.
Front Vet Sci
September 2024
Liaoning Zhongqing Xinze Biotechnology Co. Ltd., Huludao, China.
Introduction: The present study explores the effect of ginseng stem leaf (GSL) extract on the production performance, meat quality, antioxidant status, immune function, and lipid metabolism of white feathered broilers.
Methods: There were 6 replicates in each group, with 10 broilers in each replicate. In the 42 day trial, 300 AA broilers were randomly divided into five groups: control group (CON), 1.
Electrochemical approach of the reductive activation of O by a nonheme Fe complex. Some clues for the development of catalytic oxidations.
Dalton Trans
September 2024
Université Paris-Saclay, CNRS, Institut de Chimie Moléculaire et des Matériaux d'Orsay, 91400, Orsay, France.
Article Synopsis
- - The study investigates how a nonheme [Fe(L25)(MeCN)] complex activates dioxygen (O) through cyclic voltammetry, showing that coordination results in a strong Fe-O bond rather than a superoxide form.
- - An electron injection into the Fe-O adduct occurs at -700 mV, leading to the creation of Fe-peroxo and subsequently Fe-hydroperoxo upon protonation by water, with CV simulations supporting this detailed mechanism.
- - Despite the formation of the Fe-peroxo intermediate at -650 mV, low faradaic yields in oxidative bromination reactions indicate that side reactions hinder efficiency, prompting suggestions for improved catalytic methods.
Pediatric atypical teratoid/rhabdoid tumor in the cauda equina with rapid tumor progression: illustrative case.
J Neurosurg Case Lessons
August 2024
Departments of Neurosurgery and Neuro-Oncology, National Cancer Center Hospital, Tokyo, Japan.
Article Synopsis
- Atypical teratoid/rhabdoid tumor (AT/RT) is a rare and dangerous type of cancer that can sometimes occur in the spine, especially in kids.
- A 9-year-old boy had back and leg pain due to a tumor in his spine and had surgery to remove it, which was found to be AT/RT.
- After surgery and treatment, he got better and didn't have any signs of the cancer coming back after 6 months.
Orofacial antinociceptive activity of codeine-associated geraniol in mice: a controlled triple-blind study.
Braz Oral Res
August 2024
Universidade Federal da Paraíba - UFPB, Faculty of Dentistry, Department of Clinical and Social Dentistry, João Pessoa, PB, Brazil.
This is a nonclinical, controlled, and triple-blind study to investigate the effects of codeine-associated geraniol on the modulation of orofacial nociception and its potential central nervous system depressing effect in an animal model. The orofacial antinociceptive activity of geraniol in combination with codeine was assessed through the following tests: (i) formalin-induced pain, (ii) glutamate-induced pain, and (iii) capsaicin-induced pain. Six animals were equally distributed into six groups and received the following treatments, given intraperitoneally (i.
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