Perioperative cardiovascular and noncardiovascular risk in patients with colorectal cancer.

Background: One of the factors determining the success of colorectal cancer (CC) surgery is an appropriate stratification of perioperative risk.

Objective: To evaluate the prognostic significance ofperioperative risk in patients with CC, a comparison of two groups of patients--surviving and non-surviving the CC surgery was performed. Cardiovascular and noncardiovascular risk factors, diseases and complications were compared between these two groups.

Patients: 60 patients (m:30, f:30), average age: 73 ys, surviving (38), non-surviving (22).

Methods: Following parameters were compared: risk factors (arterial hypertension, diabetes mellitus, hyperlipoproteinemia, smoking or alcohol consumption, malnutrition, obesity), cardiovascular diseases (history of coronary artery disease, heart failure, brain stroke, revascularisation, chronic venous insufficiency), noncardiovascular diseases (COPD, asthma, renal insufficiency, metabolic diseases, peptic ulcer disease, chronic hepatitis, pulmonary tuberculosis, bone or kidney tuberculosis, hepatopathy), complications and laboratory parameters.

Results: Comparison of the listed parameters in non-surviving/surviving patients: bronchopneumonia (36%/4%), perineal haemorrhage (36%/4%), hepatopathy (28%/4%), renal insufficiency (50%/16%), hypoalbuminemia (50%/16%), history of acute stroke (21%/12.5%), history of brain stroke (12.5%/7%).

Conclusion: Risk factors (bronchopneumonia, perineal haemorrhage, hepatopathy, renal insufficiency, hypoalbuminemia) are markers of worse prognosis. The cardial markers (history of acute stroke and history of brain stroke) play a minor role (Tab. 10, Ref 3).