Purpose: To report a case of peripheral ulcerative keratitis and central vein occlusion as the initial manifestation of HIV infection.
Method: Case report.
Result: A 46-year-old male presented with history of pain, redness, and diminished vision of left eye. Examination revealed left eye peripheral ulcerative keratitis (PUK) and right eye central retinal vein occlusion (CRVO). The patient was found to be positive for HIV on serological evaluation.
Conclusion: Atypical ophthalmic manifestations may be the initial presenting feature in patients with HIV infection. This highlights the need for increased index of suspicion for HIV infection in young patients with PUK and/or CRVO.
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http://dx.doi.org/10.1080/09273940701572404 | DOI Listing |
BMJ Open
January 2025
Biophotonics Medicine, Universidade Nove de Julho, Sao Paulo, Brazil
Introduction: The prevention of diabetic foot ulcer (DFU) involves the classification of risk, systemic care, regular examinations, foot care, therapeutic education and adjunct treatments. Photobiomodulation (PBM) has been successfully administered for the healing of DFU and its preventive effects have drawn the interest of researchers.
Methods And Analysis: The purpose of the study is to assess the effect of PBM for the prevention of DFU through a randomised, controlled, double-blind, clinical trial.
J Community Hosp Intern Med Perspect
November 2024
Medstar Health Internal Medicine Residency Program, Baltimore, MD, USA.
The co-occurrence of inflammatory eye disease and hidradenitis suppurativa (HS) is uncommon; ocular involvement typically manifests as anterior uveitis. In this report, we present a unique case of peripheral ulcerative keratitis (PUK) where both infectious and rheumatological workup was negative, leading us to consider the possibility of an association between this condition and severe HS. As far as we are aware, there have only been six documented cases of PUK associated with HS.
View Article and Find Full Text PDFQuant Imaging Med Surg
January 2025
Division of Plastic Surgery, Johns Hopkins University, Baltimore, MD, USA.
Background And Objective: Diabetic neuropathy significantly elevates the risk of foot ulceration and lower-limb amputation, underscoring the need for precise assessment of tissue perfusion to optimize management. This narrative review explores the intricate relationship between sympathetic nerves and tissue perfusion in diabetic neuropathy, highlighting the important role of autonomic neuropathy in blood flow dynamics and subsequent compromises in tissue perfusion. The consequences extend to the development of diabetic peripheral neuropathy and related foot complications.
View Article and Find Full Text PDFVasc Med
January 2025
Department of Vascular Surgery, Leiden University Medical Center, Leiden, The Netherlands.
Foot ulceration is a significant and growing health problem worldwide, particularly due to rises in diabetes mellitus (DM) and peripheral artery disease. The prediction of ulcer healing remains a major challenge. In patients with foot ulcers, medial arterial calcification (MAC) can be present as a result of concomitant DM or chronic kidney disease and is a prognostic factor for unfavorable outcome.
View Article and Find Full Text PDFSci Rep
January 2025
Department of Endocrinology, NRS Medical College and Hospital, Kolkata, West Bengal, India.
Professionals like deep-miners and factory-workers wear specialized safety-shoes to protect against occupational hazards (OF). The risk factors, clinico-microbiologic profile and complications of diabetic foot ulcers (DFU) in these professionals remain unexplored. A cross-sectional observational study was conducted to describe the unique clinico-microbiologic profile of DFU in those wearing occupational-footwear (OF) and find risk factors for DFU related osteomyelitis in them.
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