Background: It is rapidly becoming the standard of care to employ the perioperative use of intermittent pneumatic compression (IPC) devices on the lower leg to prevent the development of deep venous thrombosis. There are instances when the anesthesiologist must apply a blood pressure cuff to the ankle in order to obtain a blood pressure reading. The purpose of this study is to determine the influence of IPC devices on non-invasive blood pressure measurements of the ankle.
Methods: We utilized the Flowtron Excel External Pneumatic Compression System Model AC550 and the Datascope Passport non-invasive blood pressure monitor Model EL, in 50 healthy volunteers ranging in ages from 23 to 35 who were free of systemic disease. The IPC devices were applied to both lower extremities and sequentially inflated. All blood pressure measurements (systolic, diastolic, and mean arterial pressure) were taken with the volunteer in the supine position, obtained in triplicate and then averaged. Blood pressure measurements were obtained at four time periods: 1) when the IPC device was placed over the ankle blood pressure cuff but not inflated (control) 2) 15 s prior to inflation of the IPC device 3) at inflation of the IPC device and 4) 15 s after the beginning of inflation of the IPC device. The difference between the averaged blood pressures and the control blood pressures were calculated. The resulting values were then converted to absolute values. The averaged absolute values were analyzed using ANOVA for repeated (paired) data.
Results: No statistical significant difference was shown between the control blood pressure measurements and any of the three sets of blood pressure measurements relative to IPC device inflation; 15 s prior, at onset, and 15 s after inflation. The p-values for systolic, diastolic, and MAP were respectively 0.872, 0.645 and 0.522. With these p-values, the power tests for each were >0.80.
Conclusion: The IPC device had no significant impact on non-invasive blood pressure measurement of the ankle in our study.
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http://dx.doi.org/10.1007/s10877-007-9100-1 | DOI Listing |
Appl Psychophysiol Biofeedback
January 2025
Department of Psychology, Brigham Young University, Salt Lake City, UT, USA.
Square and 4-7-8 breathing are popularly promoted by psychotherapists but have little empirical support. We hypothesized that breathing at 6 breaths per minute (bpm) would improve HRV, reduce blood pressure, and improve mood more than either square or 4-7-8 breathing. We also hypothesized square and 4-7-8 breathing would increase end-tidal CO (PETCO).
View Article and Find Full Text PDFJ Adolesc Health
January 2025
Center for Clinical Big Data and Statistics of the Second Affiliated Hospital Zhejiang University School of Medicine, School of Public Health Zhejiang University School of Medicine, Hangzhou, Zhejiang, China. Electronic address:
Purpose: To evaluate the effect of osilodrostat and hypercortisolism control on blood pressure (BP) and glycemic control in patients with Cushing's disease.
Methods: Pooled analysis of two Phase III osilodrostat studies (LINC 3 and LINC 4), both comprising a 48-week core phase and an optional open-label extension. Changes from baseline in systolic and diastolic BP (SBP and DBP), fasting plasma glucose (FPG), and glycated hemoglobin (HbA) were evaluated during osilodrostat treatment in patients with/without hypertension or diabetes at baseline.
Sci Rep
January 2025
Department of Neonatology, Children's Hospital of Soochow University, Suzhou, China.
This study investigated the correlation between quantitative echocardiographic characteristics within 3 days of birth and necrotizing enterocolitis (NEC) and its severity in preterm infants. A retrospective study was conducted on 168 preterm infants with a gestational age of < 34 weeks. Patients were categorized into NEC and non-NEC groups.
View Article and Find Full Text PDFChin Med J (Engl)
January 2025
Department of Metabolism and Endocrinology, National Clinical Research Center for Metabolic Diseases, Key Laboratory of Diabetes Immunology (Central South University), Ministry of Education, The Second Xiangya Hospital of Central South University, Changsha, Hunan 410011, China.
Background: Approximately 40% of individuals with diabetes worldwide are at risk of developing diabetic kidney disease (DKD), which is not only the leading cause of kidney failure, but also significantly increases the risk of cardiovascular disease, causing significant societal health and financial burdens. This study aimed to describe the burden of DKD and explore its cross-country epidemiological status, predict development trends, and assess its risk factors and sociodemographic transitions.
Methods: Based on the Global Burden of Diseases (GBD) Study 2021, data on DKD due to type 1 diabetes (DKD-T1DM) and type 2 diabetes (DKD-T2DM) were analyzed by sex, age, year, and location.
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