An alkoxide-directed alkyne-allene cross-coupling for stereoselective synthesis of 1,4-dienes.

Chem Commun (Camb)

Department of Chemistry, Yale University, New Haven, CT, USA.

Published: November 2007

A titanium alkoxide-mediated convergent coupling between internal alkynes and allenes is described for the regio- and stereocontrolled synthesis of substituted acyclic 1,4-dienes.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4319186PMC
http://dx.doi.org/10.1039/b708256hDOI Listing

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