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Long-term adoption of plow tillage and green manure improves soil physicochemical properties and optimizes microbial communities under a continuous peanut monoculture system.
Front Microbiol
January 2025
College of Agriculture, Shandong Agricultural University/National Key Laboratory of Wheat Improvement, Taian, China.
Continuous monocropping of peanuts (.) often results in yield decline and soil degradation. The combination of green manure (GM) with tillage practices has been proposed as a sustainable strategy to maintain high crop productivity and improve soil quality.
View Article and Find Full Text PDFDietary content and eating behavior in ulcerative colitis: a narrative review and future perspective.
Nutr J
January 2025
Clinical College, Hubei University of Chinese Medicine, Wuhan, Hubei, China.
Ulcerative colitis (UC) has experienced a steady increase in global incidence and prevalence recently. Current research into UC pathogenesis focuses on the complex interplay of genetic and environmental factors with the immune system and gut microbiome, leading to disruption of the intestinal barrier. Normally, the microbiome, intestinal epithelium, and immune system interact to maintain intestinal homeostasis.
View Article and Find Full Text PDFPharmacological and structural insights into nanvuranlat, a selective LAT1 (SLC7A5) inhibitor, and its N-acetyl metabolite with implications for cancer therapy.
Sci Rep
January 2025
Department of Bio-System Pharmacology, Graduate School of Medicine, Osaka University, 2-2, Yamadaoka, Suita, Osaka, 565-0871, Japan.
L-type amino acid transporter 1 (LAT1, SLC7A5), overexpressed in various cancers, mediates the uptake of essential amino acids crucial for tumor growth. It has emerged as a promising target for cancer therapy. Nanvuranlat (JPH203/KYT-0353), a LAT1 inhibitor, has shown antitumor activity in preclinical studies and efficacy in biliary tract cancer during clinical trials.
View Article and Find Full Text PDFEndosymbionts as hidden players in tripartite pathosystem of interactions and potential candidates for sustainable viral disease management.
Crit Rev Biotechnol
January 2025
Key Laboratory of Agricultural Microbiology, College of Agriculture, Guizhou University, Guiyang, P.R. China.
The convoluted relationships between plants, viruses, and arthropod vectors housing bacterial endosymbionts are pivotal in the spread of harmful plant viral diseases. Endosymbionts play key roles in: manipulating host responses, influencing insect resistance to pesticides, shaping insect evolution, and bolstering virus acquisition, retention, and transmission. This interplay presents an innovative approach for developing sustainable strategies to manage plant diseases.
View Article and Find Full Text PDFCan green finance exorcize the resource curse in China's resource-based cities? A geographically and temporally weighted regression (GTWR) analysis.
J Environ Manage
January 2025
College of Economics and Management, Fujian Agriculture and Forestry University, Fuzhou, Fujian, 350002, PR China. Electronic address:
Resource-dependent regions often face the challenge of the resource curse, which hinders sustainable development. This study investigates how green finance can address this issue, using panel data from 115 resource-based cities in China and employing a two-way fixed effects model and a Geographically and Temporally Weighted Regression (GTWR) model. The findings reveal that: First, resource-based cities in China exhibit the resource curse, characterized by significant spatiotemporal non-stationarity.
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