We evaluated problem behavior exhibited by 6 individuals with developmental disabilities using the behavioral economic conceptualization of unit price. Descriptive observations were conducted during interactions between the participants and their primary care providers in a clinical laboratory, the participants' homes, or school. Data were recorded on potential reinforcers and problem behavior. After identifying reinforcers for each participant's problem behavior by way of functional analysis, the descriptive data were analyzed retrospectively, using the cost-benefit ratio described by the concept of unit price. Results showed that demand was elastic and produced monotonic response output curves. The results represent an extension of the concept of unit price to severe problem behavior under naturally occurring environmental conditions.
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http://dx.doi.org/10.1901/jaba.2007.40-463 | DOI Listing |
J Prosthet Dent
January 2025
Associate Professor, Department of Clinical Science, College of Dentistry, Ajman University, Ajman City, United Arab Emirates.
Statement Of Problem: Different factors affect 3-dimensionally (3D) printed resin products. However, evidence on the effect of the print orientation on resin dental devices is lacking.
Purpose: The purpose of this systematic review and meta-analysis was to assess the impact of print orientation on the properties and accuracy of 3D printed implant surgical guides, occlusal devices, clear orthodontic retainers, and aligners.
Naunyn Schmiedebergs Arch Pharmacol
January 2025
Hannover Medical School, Institute of Pharmacology, D-30625, Hannover, Germany.
The increasing supply shortages of antibacterial drugs presents significant challenges to public health in Germany. This study aims to predict the future consumption of the ten most prescribed antibacterial drugs in Germany up to 2040 using ARIMA (Auto Regressive Integrated Moving Average) models, based on historical prescription data. This analysis also evaluates the plausibility of the forecasts.
View Article and Find Full Text PDFNeuropsychopharmacol Rep
March 2025
Department of Biology and Microbiology, Faculty of Medical Laboratory Technology, Khatam Al-Nabieen University, Kabul, Afghanistan.
Introduction: Substance use disorders, particularly alcohol use disorders, represent a significant public health problem, with adolescents particularly vulnerable to their adverse effects. This study examined the possible anxiolytic and antidepressant effects of biotin, a crucial vitamin for brain function, in attenuating the behavioral and neurobiological changes associated with alcohol withdrawal in adolescent rats.
Materials And Methods: Sixty male Sprague-Dawley rats were exposed to a 20% ethanol solution for 21 days, followed by a 21-day drug-free period to assess long-term behavioral and physiological changes.
Objective: To increase the number of episodes of vitamin D teaching in the primary care setting for parents of human milk-fed infants and to explore pediatric clinicians' knowledge of vitamin D supplementation in human milk-fed infants and their perception of project intervention usefulness.
Design: Quality improvement project using a quasi-experimental, pretest-posttest design.
Setting/local Problem: Despite recommendations from the American Academy of Pediatrics, vitamin D supplementation adherence rates for human milk-fed infants remain low.
Proc Natl Acad Sci U S A
January 2025
Institute of Science and Technology Austria, Klosterneuburg AT-3400, Austria.
Many biological systems operate near the physical limits to their performance, suggesting that aspects of their behavior and underlying mechanisms could be derived from optimization principles. However, such principles have often been applied only in simplified models. Here, we explore a detailed mechanistic model of the gap gene network in the embryo, optimizing its 50+ parameters to maximize the information that gene expression levels provide about nuclear positions.
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