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Short-term efficacy of laparoscopic type C radical hysterectomy by deep uterine vein approach for treatment of cervical cancer.
Afr J Reprod Health
December 2024
Department of Gynecology, The Affiliated Huai'an No.1 People's Hospital of Nanjing Medical University, Huai'an, Jiangsu 223300, China.
This was an original research. The objective of the study was to investigate the efficacy of laparoscopic type C radical hysterectomy by deep uterine vein approach in treating cervical cancer. Two hundred cases of cervical cancer were allocated into control group and intervention group.
View Article and Find Full Text PDFNeoadjuvant chemoradiation with or without PD-1 blockade in locally advanced rectal cancer: a randomized phase 2 trial.
Nat Med
January 2025
Department of General Surgery, Beijing Friendship Hospital, Capital Medical University, Beijing, China.
Radiotherapy displays unique antitumor synergism with immune checkpoint inhibitors, which is indicated by high pathological complete response (pCR) rates from single-arm trials of locally advanced rectal cancer (LARC). Here we test the efficacy and safety of the radiation-immune checkpoint inhibitor combination in patients with LARC in a phase 2, randomized trial conducted in eight major colorectal cancer centers in Beijing. In total, 186 eligible all-comer (proficient mismatch repair and deficient mismatch repair) participants were enrolled.
View Article and Find Full Text PDFRare Renal Malignancies: A Case Series Highlighting Uncommon Presentations and Their Management Strategies.
Cureus
December 2024
Department of Urology, Mamata Academy of Medical Sciences, Bachupally, IND.
This case series elucidates renal cell carcinoma characterized by three distinct presentations, necessitating individualized treatment strategies tailored to each specific circumstance. The three cases presented pertain to clear cell renal cell carcinoma. The first case involves a 44-year-old male patient with renal cell carcinoma in an ectopic kidney, an exceedingly rare occurrence with limited literature.
View Article and Find Full Text PDFNeural Network and Logistic Regression Models Based on Ultrasound Radiomics and Clinical-Pathological Features to Predict Occult Level II Lymph Node Metastasis in Papillary Thyroid Carcinoma.
Acad Radiol
January 2025
Department of General Surgery, Sir Run Run Shaw Hospital, School of Medicine, Zhejiang University, Hangzhou, Zhejiang, China (J-W.F., H.L.); Zhejiang Engineering Research Center of Cognitive Healthcare, Sir Run Run Shaw Hospital,School of Medicine, Zhejiang University, Hangzhou, China (H.L.); College of Biomedical Engineering and Instrument Science, Zhejiang University, Hangzhou, China (H.L.). Electronic address:
Rationale And Objectives: Papillary thyroid carcinoma (PTC) often metastasizes to lateral cervical lymph nodes, especially in level II. This study aims to develop predictive models to identify level II lymph node metastasis (LNM), guiding selective neck dissection (SND) to minimize unnecessary surgery and morbidity in low-risk patients.
Methods: A retrospective cohort of 313 PTC patients who underwent modified radical neck dissection (MRND) between October 2020 and January 2023 was analyzed.
Study Protocol of the Korean EGFR Registry: A Multicenter Prospective and Retrospective Cohort Study in Nonsmall Cell Lung Cancer Patients With EGFR Mutation.
Clin Respir J
January 2025
Division of Pulmonology, Department of Internal Medicine, Seoul St. Mary's Hospital, Catholic University of Korea, Seoul, Republic of Korea.
Introduction: The provision of treatment for epidermal growth factor receptor (EGFR)-mutated nonsmall cell lung cancer (NSCLC) patients has increased in Korea. However, multicenter studies on the clinicopathologic dataset and treatment outcomes, using a large-scale dataset, have not been conducted. The current study is a prospective and retrospective multicenter observational cohort study that registers all stages of EGFR-mutated NSCLC patients.
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