Introduction: Atrial tachycardias are a common problem following the surgical repair of complex congenital heart defects (CHD) and have a poor response to medication. The aim of this study was to describe the results of the treatment of such tachycardias with radiofrequency ablation in our hospital.
Methods: A retrospective study was performed of the medical records and electronically stored data from electrophysiological studies (EPS) and ablation procedures in patients with atrial tachycardias following the surgical repair of CHD. Established electrophysiological techniques were used in all patients, while newer three-dimensional imaging methods were also employed in some cases. Ablation was carried out using a radiofrequency generator and catheters with a 4-10 mm terminal electrode.
Results: Twenty-two patients aged 11-45 years (30.6 +/- 10.8), including 9 women, underwent an EPS and ablation of atrial tachycardias after the surgical repair of CHD. All had recurrent tachycardias refractory to antiarrhythmic medication. The anatomical diagnoses were tetralogy of Fallot (8), transposition of the great arteries (6), single ventricle (3), and other (5). Most patients had typical atrial flutter and/or incisional atrial reentrant tachycardia. The initial success rate of ablation for all arrhythmias was 88% in patients with tetralogy of Fallot, 83% for transposition of the great arteries, 66% for single ventricle, and 80% for the other diagnoses. Three-dimensional imaging was of significant assistance in mapping and ablation and in reducing the duration of fluoroscopy. Two vascular complications (femoral arteriovenous fistulae) were observed. The tachycardia recurrence rate was 54%. After repeated procedures, 59% of patients were free of arrhythmias and antiarrhythmic medications. No patient with a single ventricle remained free of arrhythmias during follow up, while in the other groups the arrhythmia/drug-free rate was 66-75%. Two patients with unsuccessful ablation died, one from heart failure and the other because of the tachycardia.
Conclusions: Atrial tachycardias in patients with surgically treated CHD are associated with increased morbidity and mortality. Radiofrequency ablation has satisfactory results. In spite of the high relapse rate, a significant number of patients can become free of arrhythmias after repeat procedures.
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J Clin Med
December 2024
Department of Cardiology, Angiology and Intensive Care Medicine, Deutsches Herzzentrum der Charité (DHZC), Campus Virchow-Klinikum, Augustenburger Platz 1, 13353 Berlin, Germany.
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View Article and Find Full Text PDFJ Clin Med
December 2024
Institut für Forschung und Lehre (IFL), Department of Molecular and Experimental Cardiology, Ruhr-University Bochum, 44791 Bochum, Germany.
Troponin level elevation without an obstructive culprit lesion is caused by heterogenous entities. The effect of aging on this condition has been poorly investigated. After screening 24,775 patients between 2010 and 2021, this study included a total of 373 patients with elevated troponin levels without an obstructive culprit lesion or suspected myocardial infarction with non-obstructive coronary arteries (MINOCAs) categorized into four age groups containing 78 patients (<51 years), 72 patients (51-60 years), 81 patients (61-70 years), and 142 patients (>70 years).
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Adult Congenital Heart Disease and Congenital and Familial Arrhythmias Unit, Monaldi Hospital, Leonardo Bianchi Street, 80131 Naples, Italy.
: Angiotensin receptor neprilysin inhibitor (ARNI) and sodium-glucose co-transporter 2 inhibitors (SGLT2i) are essential medications in heart failure (HF) therapy, and their potential antiarrhythmic effects have been reported. Recently, ARNI and SGLT2i use for HF in adult congenital heart disease (ACHD) has been studied. However, whether any beneficial effects may be achieved on the arrhythmic burden in the complex population of ACHD with a systemic right ventricle (sRV) is still to be determined.
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Douala Gyneco-obstetric and Pediatric Hospital/University of Douala, Douala, Cameroon.
J Cardiovasc Electrophysiol
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Cardiology Division, Geneva University Hospitals, Geneva, Switzerland.
Typical atrial flutter (AFL), defined as cavotricuspid isthmus (CTI)-dependent macro-re-entrant atrial tachycardia, often causes debilitating symptoms, and is associated with increased incidence of atrial fibrillation, stroke, heart failure, and death. Typical AFL occurs in patients with atrial remodeling and shares risk factors with atrial fibrillation. It is also common in patients with a history of prior heart surgery or catheter ablation.
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