AI Article Synopsis
- The study aimed to assess how a calcium phosphate (CaP) coating affects bone growth around specific titanium implants over time.
- The research involved implanting coated and uncoated Ti-6Al-4V implants in rabbits and analyzing them at various healing intervals using advanced imaging techniques.
- Results showed that CaP-coated implants encouraged significant bone growth in direct contact with the coating, indicating good stability and integration despite some layer resorption over time.
Article Abstract
Objective: To observe the long-term impact of calcium phosphate (CaP) sol-gel coating on bone growth around porous-surfaced implant.
Methods: The porous-surfaced Ti-6Al-4V implants were prepared with the addition of a thin film of CaP sol-gel coating, and implanted into the tibiae of 8 rabbits, each with two implants. Implanted sites were allowed to heal for 2, 8, 12, and 24 weeks, after which specimens were obtained for scanning electron microscope analysis using the freeze-fracture technique.
Results: The sol-gel coated implants recovered by freeze-fracture technique showed extensive bone growth from the endosteum along the implant surface. The bone was in direct contact with the CaP layer. The cement line-like layer was clearly demonstrated to be an intervening electron dense afibrillar layer between the CaP coat and the overlying newly deposited bone. The stability and osseointegration of the porous-surfaced implants seemed not to be affected by the osteoclastic resorption of CaP layer occurred during 24 weeks of healing.
Conclusion: Based on the findings in the long-term observation, the addition of a thin layer of CaP promotes an extensive osseointegrated interface between the porous-surfaced Ti-6Al-4V implants and the newly deposited bone.
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