Some features of lactase tolerance were investigated in representatives of varying groups of indigenous population in Siberia-Mansi, Khanty, Nenets, Buryats. The indirect method was used to evaluate lactase activity. A total of 92 subjects were investigated. It was found that 32% of the representatives of the Urals population group and 53% of Buryats were capable of lactase assimilating. The data obtained correspond to the cultural-genetic hypothesis on the nature of lactase tolerance in the representatives of different ethnic groups.
Download full-text PDF |
Source |
|---|
Publication Analysis
Top Keywords
Similar Publications
H4K20me3-Mediated Repression of Inflammatory Genes Is a Characteristic and Targetable Vulnerability of Persister Cancer Cells.
Cancer Res
January 2025
Institute for Research in Biomedicine (IRB Barcelona), Barcelona Institute of Science and Technology (BIST), Barcelona, Spain.
Anticancer therapies can induce cellular senescence or drug-tolerant persistence, two types of proliferative arrest that differ in their stability. While senescence is highly stable, persister cells efficiently resume proliferation upon therapy termination, resulting in tumor relapse. Here, we used an ATP-competitive mTOR inhibitor to induce and characterize persistence in human cancer cells of various origins.
View Article and Find Full Text PDFEffect of Semaglutide on Physical Function, Body Composition, and Biomarkers of Aging in Older Adults With Overweight and Insulin Resistance: Protocol for an Open-Labeled Randomized Controlled Trial.
JMIR Res Protoc
September 2024
Center for Translational Geroscience, Department of Medicine, Cedars-Sinai Medical Center, Los Angeles, CA, United States.
Background: Older adults with type 2 diabetes mellitus (T2DM) or prediabetes are at increased risk of adverse changes in body composition, physical function, and aging-related biomarkers compared to those with normal glucose tolerance. Semaglutide is a glucagon-like peptide 1 receptor agonist that has been approved for T2DM and chronic weight management. Although semaglutide is effective for weight loss and T2DM management, its effects on lean body mass, physical function, and biomarkers of aging are understudied in older adults.
View Article and Find Full Text PDFSelf-Perceived Lactose Intolerance Versus Confirmed Lactose Intolerance in Irritable Bowel Syndrome: A Systematic Review.
J Gastrointestin Liver Dis
September 2024
2nd Medical Department, Iuliu Hatieganu University of Medicine and Pharmacy, Cluj-Napoca, Romania.
Article Synopsis
- - DGBI, including IBS, affects a large portion of the population, and while lactose intolerance is common in adults, self-reported symptoms often exaggerate the problem, affecting dietary choices and overall quality of life.
- - A systematic review analyzed six studies involving 845 participants, highlighting that self-reported lactose intolerance has variable and only moderate accuracy compared to objective testing methods like hydrogen breath tests, leading to confusion in diagnosis.
- - The review emphasizes the need for objective diagnostic tools and points out that lactose-free diets should not be universally recommended for IBS patients without clear evidence of lactose intolerance.
RpoS sigma factor mediates adaptation and virulence in Vibrio mimicus.
Int J Biol Macromol
November 2024
College of Animal Science and Technology, Yangzhou University, Yangzhou 225009, China. Electronic address:
The alternative sigma factor RpoS functions as a regulator of stress and virulence response in numerous bacterial species. Vibrio mimicus is a critical opportunistic pathogen causing huge losses to aquaculture. However, the exact role of RpoS in V.
View Article and Find Full Text PDFGenomic insights of Lactiplantibacillus plantarum CNPC024: a potential probiotic strain producing immune-boosting tryptophan-derived metabolites.
Braz J Microbiol
December 2024
Department of Animal Science, College for Agricultural Sciences, Federal University of Paraiba (CCA/UFPB), Areia, PB, 58397-000, Brazil.
Article Synopsis
- Probiogenomics helps analyze probiotic bacteria, such as Lactiplantibacillus plantarum CNPC024, to understand how they benefit the host and ensure their safety for use.
- The study sequenced the genome of L. plantarum CNPC024, revealing a 3.2 Mb draft genome with 99% similarity to other probiotic L. plantarum strains.
- Key findings include its ability to withstand harsh conditions, produce β-galactosidase for lactose intolerance, lack transferable antibiotic-resistance genes, and produce bacteriocins, along with metabolic pathways that may influence the host's immune system.
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!