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Pathocycles.
Fungal Genet Biol
January 2008
Department of Molecular Biology and Biotechnology, Sheffield University, Western Bank, Sheffield, S10 2TN, UK.
Pathocycles: Ustilago maydis as a model to study the relationships between cell cycle and virulence in pathogenic fungi.
Mol Genet Genomics
September 2006
Departamento de Biotecnología Microbiana, Centro Nacional de Biotecnología-CSIC, Campus de Cantoblanco-UAM, 28049, Madrid, Spain.
Activation of virulence in pathogenic fungi often involves differentiation processes that need the reset of the cell cycle and induction of a new morphogenetic program. Therefore, the fungal capability to modify its cell cycle constitutes an important determinant in carrying out a successful infection. The dimorphic fungus Ustilago maydis is the causative agent of corn smut disease and has lately become a highly attractive model in addressing fundamental questions about development in pathogenic fungi.
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