AI Article Synopsis
- * Pregnant women who don't get enough iodine might have problems that can hurt their baby's brain development, and this can happen without obvious signs.
- * The American Thyroid Association says women should take 150 micrograms of iodine every day while they are pregnant or breastfeeding, and also use iodized salt to stay healthy.
Article Abstract
Iodine deficiency remains the most frequent cause worldwide, after starvation, of preventable mental retardation in children. It causes maternal hypothyroxinemia, which affects pregnant women even in apparently iodine-sufficient areas, and often goes unnoticed because L-thyroxine (T4) levels remain within the normal range, and thyroid-stimulating hormone (TSH) is not increased. Even a mild hypothyroxinemia during pregnancy increases the risk of neurodevelopmental abnormalities, and experimental data clearly demonstrate that it damages the cortical cytoarchitecture of the fetal brain. The American Thyroid Association (ATA) recommends a supplement of 150 microg iodine/day during pregnancy and lactation, in addition to the use of iodized salt. We discuss the importance of iodine supplementation to ensure adequate T4 levels in all women who are considering conception and throughout pregnancy and lactation.
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| http://dx.doi.org/10.1016/j.tem.2007.08.009 | DOI Listing |
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