Purpose: The scope of existing pharmacist-managed inpatient anticoagulation services and the roles and responsibilities of the pharmacists involved were studied.
Methods: A general query regarding the provision of inpatient anticoagulation services was sent by e-mail to members of the American College of Clinical Pharmacists practice and research networks for cardiology, critical care, and general internal medicine. Those individuals whose institutions had such services were sent a written questionnaire and asked to describe the scope of the services provided. Data collected included a description of the type of service model and the management strategies for seven different antithrombotic agents: warfarin, unfractionated heparin, low-molecular-weight heparin, fondaparinux, argatroban, lepirudin, and bivalirudin. Survey results were entered into a database and sent to all participants for use as a resource.
Results: Of the 33 respondents to the initial e-mail, 25 completed the written questionnaire. A variety of service models were used, most of which were developed and implemented within the past seven years. The majority of services (92%) were consultation based, many of which incorporated daily pharmacist rounds. Less than half of the services were under the supervision of a physician, and only four services involved a multidisciplinary team. In addition, the management of individual antithrombotic agents varied between services, including the automatic management of all patients receiving targeted agents, strict institution-specific protocols, and general guidelines. All but one service provided educational opportunities for students and residents.
Conclusion: Inpatient anticoagulation services described by survey respondents varied in design, structure, and level of responsibility of pharmacists.
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http://dx.doi.org/10.2146/ajhp070213 | DOI Listing |
J Thromb Haemost
January 2025
Department of Health Sciences, Warwick Medical School, University of Warwick, Coventry, United Kingdom; Department of Geratology, Oxford University Hospitals NHS Foundation Trust, Oxford, United Kingdom.
Background: Same-day emergency care (SDEC) is an expanding area of hospital acute medical care. It aims to minimize delays and manage medical emergency patients within the same day, enabling hospitalization to be avoided; the expectation is that the patients would have required inpatient hospitalization in the absence of the SDEC service. Venous thromboembolism (VTE) prevention is a key medical inpatient safety measure.
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December 2024
Hepatology Unit, Department of Infectious Diseases, Nanfang Hospital, Southern Medical University, Guangzhou510515,China.
To compare the effectiveness and safety profile of centrifugal and membrane plasma separation model in artificial liver therapy with a dual plasma molecular adsorption system (DPMAS). A retrospective study was conducted. Data of inpatients with liver failure who were treated with DPMAS therapy in the Liver Disease Center of Nanfang Hospital, Southern Medical University, from October 2022 to June 2024 were included.
View Article and Find Full Text PDFClin Appl Thromb Hemost
January 2025
Department of Pharmacy Practice, College of Pharmacy, Princess Nourah bint Abdulrahman University, Riyadh, Saudi Arabia.
Deep vein thrombosis (DVT) is a leading cause of death disability. DVT can be classified based on the location and extent of the clot into isolated distal DVT (iDDVT), isolated proximal DVT (iPDVT), or mixed DVT. The aim of this study is to explore the baseline characteristics and clinical outcomes of patients with different types of DVT.
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February 2025
Department of Urology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan 450001, P.R. China.
Warfarin is a commonly employed anticoagulant drug aimed at rapidly reaching the optimal international normalized ratio (INR), potentially reducing the hospitalization time in clinical settings. However, limited research has been conducted on the influencing factors and the safety implications of promptly reaching the target INR range in patients with valvular heart disease who have undergone valve replacement or repair. The present study aimed to assess the factors related to the safety considerations of rapidly reaching the target INR range in patients treated with warfarin.
View Article and Find Full Text PDFVasc Med
January 2025
Department of Practice, Sciences, and Health Outcomes Research, School of Pharmacy, University of Maryland, Baltimore, MD, USA.
Background: Venous thromboembolism (VTE) can lead to significant healthcare resource utilization (HcRU) and costs. First-line treatments such as direct-acting oral anticoagulants (DOAC) and low molecular weight heparin (LMWH) are utilized for VTE management. There are limited observational studies to determine which first-line drug for VTE is associated with lower HcRU and cost.
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