Neurotoxicity of tryptophan metabolites.

Biochem Soc Trans

Division of Neuroscience and Biomedical Systems, Institute of Biomedical and Life Sciences, West Medical Building, University of Glasgow, Glasgow G12 8QQ, U.K.

Published: November 2007

The metabolism of tryptophan by the kynurenine pathway leads to the production of several neurotoxic compounds, some of which have been associated with neurological disorders. Recent investigation of some relevant compounds in this pathway has provided further evidence of their neurotoxicity.

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Source
http://dx.doi.org/10.1042/BST0351287DOI Listing

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