We report on a case of rhabdomyosarcoma of the bladder in an adult patient. A 65-year-old woman presented with macroscopic hematuria. Ultrasonography revealed a large bladder tumor and severe hydronephrosis of the right kidney. Computed tomography (CT) confirmed these findings and revealed extravesical tumor extension. Cystoscopic biopsy of the tumor showed botryoid rhabdomyo- sarcoma. The patient's local and general conditions did not allow any adjuvant treatment. The patient died of disease 6 months later.
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J Urol
December 2024
Department of Urology, Boston Children's Hospital, Boston, Massachusetts.
Purpose: Genitourinary rhabdomyosarcoma (GU-RMS) often requires multimodal therapy treatment including radiation, chemotherapy, and radical surgery for disease control. The long-term effects of the disease and associated treatments are unclear. We sought to investigate the long-term genitourinary quality of life for adult survivors of pediatric GU-RMS.
View Article and Find Full Text PDFWorld J Urol
December 2024
Department of Urology, University of Rochester Medical Center, 601 Elmwood Avenue, Box 668, Rochester, NY, 14642, USA.
Purpose: Pediatric Rhabdomyosarcoma (RMS) is a morbid and often lethal condition characterized by a paucity of clinical data. Beyond a detailed risk categorization system, it is unclear if genitourinary (GU) sites (bladder/prostate, paratesticular, female organs) have outcomes distinct from non-GU sites. This study pools primary data from phase-3 clinical trials involving pediatric RMS to evaluate this question.
View Article and Find Full Text PDFJ Med Case Rep
November 2024
Department of Medical Oncology, The First Affiliated Hospital of Xiamen University, Xiamen, 361003, China.
Introduction: Sarcomas with muscle differentiation (for example, rhabdomyosarcoma, leiomyosarcoma, and pleomorphic sarcoma) are uncommon in the adult bladder.
Case Presentation: In this case report, we describe a 69-year-old Chinese male patient who presented to the urology outpatient clinic because of intermittent full-course macroscopic hematuria for 10 days. A B ultrasound indicated hypoechoic nodules in the right upper wall of the bladder.
Transl Androl Urol
September 2024
Division of Urology, Department of Surgery, The University of Hong Kong-Shenzhen Hospital, Shenzhen, China.
Background: Embryonal rhabdomyosarcoma (ERMS) of the prostate is a rare and aggressive malignant tumor in adults with a poor prognosis in general. The main presenting symptoms are dysuria and acute urinary retention. Prostate ERMS is easily misdiagnosed, which leads to delays in treatment.
View Article and Find Full Text PDFInt J Radiat Oncol Biol Phys
September 2024
Department of Radiation Oncology, Gustave Roussy Cancer Campus, Cancer Center, Villejuif, France; INSERM 1030 Molecular radiotherapy, Gustave Roussy Cancer Campus, Villejuif, France. Electronic address:
Purpose: Rhabdomyosarcoma (RMS) is the most common soft tissue cancer in children. Around 15% of RMS involve the bladder and/or prostate (BP). Overall survival is around 85%.
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