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Rapid Development and Rupture of an Infected Intracranial Aneurysm Caused by Streptococcus salivarius Meningitis: A Case Report.
Cureus
November 2024
Department of Pediatrics, Hyogo Prefectural Amagasaki General Medical Center, Amagasaki, JPN.
The clinical manifestation of intracranial mycotic aneurysms (ICMAs), which are rare but carry high risks of rupture and early mortality, remains poorly understood. We present a case of an ICMA that rapidly developed and ruptured after the diagnosis of meningitis caused by (), which rarely causes bacterial meningitis. A 54-year-old man presented with a headache that worsened on coughing, without altered consciousness or vomiting.
View Article and Find Full Text PDFGlobal burden of tuberculous meningitis in children aged 0-14 years in 2019: a mathematical modelling study.
Lancet Glob Health
January 2025
Sheffield Centre for Health and Related Research, School of Medicine and Population Health, University of Sheffield, Sheffield, UK.
Background: Tuberculous meningitis is fatal if untreated and can lead to lifelong neurological sequelae. However, to our knowledge, there are no data on the number of children affected by this disease. We aimed to estimate the global disease burden and attributable mortality of childhood tuberculous meningitis by WHO regions, age groups, treatment status, and HIV status in 2019.
View Article and Find Full Text PDFMeningitis due to Gemella sp. in a patient with severe ENT conditions: case report and review of the literature.
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Laboratoire de Microbiologie, Centre Hospitalier de Valenciennes, Valenciennes, F-59300, France.
In June 2022, a 73-year-old man with a history of laryngeal and esophageal carcinoma was admitted to the emergency unit with sudden fever, confusion, and general condition deterioration. Initial assessments showed a fever of 38.5 °C, elevated C-reactive protein (CRP) at 209 mg/L, and a neutrophil count of 10.
View Article and Find Full Text PDFAdvancing cryptococcal treatment: The role of nanoparticles in mitigating antifungal resistance.
Curr Res Microb Sci
November 2024
Department of Microbiology, SRM Medical College Hospital and Research Centre, SRM Institute of Science and Technology, Kattankulathur 603203, Chennai, Tamil Nadu, India.
Article Synopsis
- Cryptococcus is a dangerous fungal pathogen responsible for nearly 250,000 cases and 181,000 deaths from cryptococcal meningitis each year, particularly impacting vulnerable populations like HIV patients and organ transplant recipients.
- Treating cryptococcal infections is complicated by antifungal resistance, emphasizing the need for effective control measures and innovative treatment strategies.
- Nanoparticle-based therapies show promise as advanced antifungal solutions, highlighting the necessity for further research to combat antifungal resistance and improve treatment for cryptococcal infections.
Pneumococcal Endocarditis, Sepsis, and Meningitis in an Immunocompromised Patient: A Case Study.
Am J Case Rep
December 2024
Department of Medicine, Emory University School of Medicine, Atlanta, GA, USA.
BACKGROUND Streptococcus pneumoniae is an uncommon but serious cause of infective endocarditis (IE), particularly in immunocompromised individuals, such as those with untreated HIV. When pneumococcal IE occurs, it is associated with high morbidity and mortality due to the high prevenance of complications such as acute valvular destruction and septic embolization. Therefore, early recognition and prompt surgical intervention are paramount to improving outcomes.
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