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| http://dx.doi.org/10.1155/2007/256945 | DOI Listing |
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Incident Myocardial Infarction, Heart Failure, and Oncologic Outcomes in Breast Cancer Survivors.
JACC CardioOncol
December 2024
Institute of Health Policy, Management and Evaluation, University of Toronto, Toronto, Ontario, Canada.
Background: Cardiovascular disease (CVD) is associated with higher rates of incident cancer. Data are scarce regarding the association of incident CVD with oncologic outcomes after a cancer diagnosis.
Objectives: This study sought to determine whether incident myocardial infarction (MI) or heart failure (HF) in breast cancer survivors is associated with oncologic outcomes.
Evaluating ADHD medication trial representativeness: a Swedish population-based study comparing hypothetically trial-eligible and trial-ineligible individuals.
Lancet Psychiatry
January 2025
Developmental Evidence synthesis, Prediction, Implementation lab, Centre for Innovation in Mental Health, Faculty of Environmental and Life Sciences, University of Southampton, Southampton, UK; Hampshire and Isle of Wight NHS Foundation Trust, Southampton, UK; Clinical and Experimental Sciences (CNS and Psychiatry), Faculty of Medicine, University of Southampton, Southampton, UK; Hassenfeld Children's Hospital at NYU Langone, New York University Child Study Center, New York City, NY, USA; DiMePRe-J-Department of Precision and Regenerative Medicine-Jonic Area, University of Bari Aldo Moro, Bari, Italy.
Background: Randomised controlled trials (RCTs) evaluating ADHD medications often use strict eligibility criteria, potentially limiting generalisability to patients in real-world clinical settings. We aimed to identify the proportion of individuals with ADHD who would be ineligible for medication RCTs and evaluate differences in treatment patterns and clinical and functional outcomes between RCT-eligible and RCT-ineligible individuals.
Methods: We used multiple Swedish national registries to identify individuals with ADHD, aged at least 4 years at the age of diagnosis, initiating pharmacological treatment between Jan 1, 2007, and Dec 31, 2019, with follow-up up to Dec 31, 2020.
Cost-Effectiveness of Breast Cancer Screening Using Digital Mammography in Canada.
JAMA Netw Open
January 2025
Medical Oncology, The Ottawa Hospital Cancer Centre, University of Ottawa Faculty of Medicine, Ottawa, Ontario, Canada.
Importance: Evolving breast cancer treatments have led to improved outcomes but carry a substantial financial burden. The association of treatment costs with the cost-effectiveness of screening mammography is unknown.
Objective: To determine the cost-effectiveness of population-based breast cancer screening in the context of current treatment standards.
Outcomes of Total Ankle Replacement Versus Ankle Arthrodesis for the Treatment of End-Stage Ankle Arthritis: A Concise Follow-up, at a Minimum of 10 Years, of a Previous Report.
J Bone Joint Surg Am
December 2024
Division of Orthopaedic Surgery, St. Michael's Hospital, Toronto, Ontario, Canada.
Article Synopsis
- Study aimed to compare long-term clinical outcomes of total ankle replacement (TAR) and ankle arthrodesis (AA) in patients with end-stage ankle arthritis, using validated scoring tools.
- A cohort of 211 patients with a minimum follow-up of 10 years found differences in demographics and surgery reoperation rates between the AA and TAR groups; AA patients had fewer subsequent surgeries (70% vs. 58%).
- Overall, both TAR and AA groups exhibited similar functional outcomes over the long term, suggesting that the choice between these treatments should be tailored to individual patient conditions.
The explanatory role of psychological distress in the link between role blurring and relationship satisfaction: A dyadic study.
J Marital Fam Ther
January 2025
Department of Psychology, Université de Sherbrooke, Sherbrooke, Quebec, Canada.
Role blurring has been associated with negative outcomes, such as anxiety and stress. Paulin et al.'s study found that role blurring is linked to lower relationship satisfaction through higher psychological distress.
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