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The gut microbiome is a complex system that directly interacts with and influences many systems in the body. This delicate balance of microbiota plays an important role in health and disease and is highly influenced by lifestyle factors and the surrounding environment. As further research emerges, understanding the full potential of the gut microbiome and the impact of using nutraceuticals to positively influence its function may open the door to greater therapeutic outcomes in the treatment and prevention of disease.
View Article and Find Full Text PDFTargeting Ketone Body Metabolism Improves Cardiac Function and Hemodynamics in Patients With Heart Failure: A Systematic Review and Meta-Analysis.
Nutr Rev
January 2025
Department of Clinical Medicine, School of Medicine, Shaoxing University, Shaoxing, Zhejiang 312000, P. R. China.
Context: The impacts of elevated ketone body levels on cardiac function and hemodynamics in patients with heart failure (HF) remain unclear.
Objective: The effects of ketone intervention on these parameters in patients with HF were evaluated quantitatively in this meta-analysis.
Data Sources: We searched the PubMed, Cochrane Library, and Embase databases for relevant studies published from inception to April 13, 2024.
Chrysanthemum extract mitigates high-fat diet-induced inflammation, intestinal barrier damage and gut microbiota disorder.
Food Funct
January 2025
Institute of Food Nutrition and Quality Safety, College of Life Sciences, China Jiliang University, Hangzhou, Zhejiang, 310018, China.
An effective intervention for obesity without side effects is needed. Chrysanthemum may be the preferred choice due to its influence in the improvement of glycolipid metabolism. This study assessed the efficacy of chrysanthemum and its flavonoids in mitigating high-fat diet (HFD) induced obesity, focusing on the integrity of the intestinal barrier, inflammation, and gut microbiota.
View Article and Find Full Text PDFDelving Into lncRNA-Mediated Regulation of Autophagy-Associated Signaling Pathways in the Context of Breast Cancer.
Cell Biol Int
January 2025
Department of Medical Laboratory Technology, College of Medical Technology, The Islamic University, Najaf, Iraq.
Breast cancer is a multifaceted and prevalent malignancy, impacting a considerable proportion of women globally. Numerous signaling pathways intricately regulate cellular functions such as growth, proliferation, and survival. Among the various regulators, lncRNAs have emerged as significant players despite their inability to encode proteins.
View Article and Find Full Text PDFFriends' influence on Adolescents' loss of control eating: The moderating role of self-esteem, fear of negative evaluation, and body dissatisfaction.
J Res Adolesc
March 2025
Behavioural Science Institute, Radboud University, Nijmegen, The Netherlands.
Friends' influence may importantly contribute to the development of adolescent disordered eating behaviors. However, little is known about the influence of friends on loss of control eating. This study investigated whether friend-reported loss of control eating was associated with changes in adolescents' own loss of control eating 1 year later and tested whether adolescents with lower self-esteem, higher fear of negative evaluation, and higher body dissatisfaction were more susceptible to friends' influence.
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