A PHP Error was encountered

Severity: Warning

Message: file_get_contents(https://...@pubfacts.com&api_key=b8daa3ad693db53b1410957c26c9a51b4908&a=1): Failed to open stream: HTTP request failed! HTTP/1.1 429 Too Many Requests

Filename: helpers/my_audit_helper.php

Line Number: 176

Backtrace:

File: /var/www/html/application/helpers/my_audit_helper.php
Line: 176
Function: file_get_contents

File: /var/www/html/application/helpers/my_audit_helper.php
Line: 250
Function: simplexml_load_file_from_url

File: /var/www/html/application/helpers/my_audit_helper.php
Line: 1034
Function: getPubMedXML

File: /var/www/html/application/helpers/my_audit_helper.php
Line: 3152
Function: GetPubMedArticleOutput_2016

File: /var/www/html/application/controllers/Detail.php
Line: 575
Function: pubMedSearch_Global

File: /var/www/html/application/controllers/Detail.php
Line: 489
Function: pubMedGetRelatedKeyword

File: /var/www/html/index.php
Line: 316
Function: require_once

Efficient event-driven simulation of excitable hybrid automata. | LitMetric

Efficient event-driven simulation of excitable hybrid automata.

Conf Proc IEEE Eng Med Biol Soc

Comput. Sci. Dept., Stony Brook Univ., NY 11790, USA.

Published: March 2008

We present an efficient, event-driven simulation framework for large-scale networks of excitable hybrid automata (EHA), a particular kind of hybrid automata that we use to model excitable cells. A key aspect of EHA is that they possess protected modes of operation in which they are non-responsive to external inputs. In such modes, our approach takes advantage of the analytical solution of the modes' linear differential equations to eliminate all integration steps, and therefore to dramatically reduce the amount of computation required. We first present a simple simulation framework for EHA based on a time-step integration method that follows naturally from our EHA models. We then present our event-driven simulation framework, where each cell has an associated event specifying both the type of processing next required for the cell and a time at which the processing must occur. A priority queue, specifically designed to reduce queueing overhead, maintains the correct ordering among events. This approach allows us to avoid handling certain cells for extended periods of time. Through a mode-by-mode case analysis, we demonstrate that our event-driven simulation procedure is at least as accurate as the time-step one. As experimental validation of the efficacy of the event-driven approach, we demonstrate a five-fold improvement in the simulation time required to produce spiral waves in a 400-x-400 cell array.

Download full-text PDF

Source
http://dx.doi.org/10.1109/IEMBS.2006.260402DOI Listing

Publication Analysis

Top Keywords

event-driven simulation
16
hybrid automata
12
simulation framework
12
efficient event-driven
8
excitable hybrid
8
simulation
6
simulation excitable
4
automata efficient
4
event-driven
4
framework large-scale
4

Similar Publications

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!