Another nail in the tobacco coffin.

Int J Tuberc Lung Dis

Published: October 2007

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Introduction: Symptomatic interlocking screws are common after intramedullary nail fixation of tibia fractures. Low-profile headless interlocking screws recently became available and could potentially reduce the rate of symptomatic screws. The purpose of this study was to compare the rate of symptomatic screws and screw removals between these screw types.

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Predictors for 1-year mortality in geriatric patients following fragile intertrochanteric fracture surgery.

J Orthop Surg Res

October 2024

Department of Emergency Surgery, Affiliated Hospital of Jining Medical University, No. 89, Guhuai Road, Jining City, 272029, Shandong Province, China.

Objective: To investigate the risk factors influencing 1-year mortality after intramedullary nail fixation for fragile intertrochanteric fracture in elderly individuals.

Methods: The medical records of 622 consecutive elderly patients (aged ≥ 65 years) with fragile intertrochanteric fractures treated with proximal femoral nail anti-rotation (PFNA) and followed-up were retrospectively analyzed. The patients were divided into death and survival groups according to their survival status within 1 year after surgery, and the differences in age, sex, region of residence, tobacco use, alcohol use, body mass index (BMI), comorbidities (hypertension, diabetes mellitus, coronary heart disease, stroke, dementia, chronic obstructive pulmonary disease, pneumonia), preoperative hemoglobin, preoperative albumin, deep vein thrombosis, fracture type (AO classification), injury-to-surgery time, American Society of Anesthesiologists (ASA) score, anesthesia modality, duration of surgery, intraoperative blood loss, and blood transfusion were compared.

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  • - Botryosphaeria dothidea is mainly known for causing diseases in woody plants, like stem canker and dieback, but has also been linked to damaging field crops such as soybeans, tobacco, and sugar beets.
  • - In a survey conducted in Serbia in September 2023, 3% of sugar beet samples showed severe root rot symptoms, with dark brown lesions and completely rotted roots indicating possible infection by B. dothidea.
  • - Two fungal isolates were obtained and identified through their growth characteristics and DNA analysis, confirming their identity as B. dothidea, consistent with previously documented descriptions of the pathogen.
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Cigarette Smoke Exposure Impairs Fracture Healing in a Rat Model: Preferential Impairment of Endochondral Over Membranous Healing.

J Biomech Eng

January 2025

Department of Orthopaedics and Physical Medicine, Medical University of South Carolina, Bioengineering Building 227, 68 President Street, Charleston, SC 29425; Department of Orthopaedics, Dartmouth-Hitchcock Medical Center and Geisel School of Medicine at Dartmouth, 1 Medical Center Drive, Lebanon, NH 03756.

Article Synopsis
  • Cigarette smoking negatively impacts the healing process of fractures, specifically delaying healing and increasing the risk of nonunion.
  • The study tested how cigarette smoke affects two types of bone healing (intramembranous vs. endochondral) using rat models with femur fractures treated with different methods.
  • Results showed that fractures treated with compression plating healed faster and more completely than those treated with intramedullary nailing, particularly in smoke-exposed animals, suggesting better surgical outcomes for smokers if compression plating is used.*
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  • This study evaluated modified Radiographic Union Scale for Tibia (mRUST) scores over time in patients with distal femur fractures treated with intramedullary nails, to identify factors influencing healing and possible reoperation.
  • Conducted in ten Level I Trauma Centers, the research included 155 fractures from 152 patients, focusing on mRUST scores at 3, 6, and 12 months post-surgery, with the primary goal of finding predictors for union timing.
  • Results showed that a 3-month mRUST score of ≤8 indicated a higher chance of reoperation, and factors such as tobacco use and open fractures correlated with delayed healing times.
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