Synthesis of a promising immunosuppressant: FR252921.

Org Lett

Laboratoire de Chimie Organique, ESPCI, Centre National de la Recherche Scientifique, 10 rue Vauquelin, Paris Cedex 05, France.

Published: November 2007

A concise and highly convergent synthesis of the promising immunosuppressant FR252921 was achieved by using optically active titanium complexes to control the configuration of the three stereogenic centers.

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Source
http://dx.doi.org/10.1021/ol702110kDOI Listing

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