Aim: Due to new medical knowledge and legal restrictions, it is increasingly difficult to run a traditional allogenic bone bank so that alternative bone substitutes and methods of processing are being sought worldwide.
Method: In a prospective clinical study, the biological efficacy of thermodisinfected and then cryopreserved allogenic bank bone was investigated in 19 acetabular revisions in 18 patients. Simultaneously a newly developed titanium reconstruction ring was used. Any revision was regarded as an end point and the follow-up with radiological and clinical results were recorded.
Results: The mean follow-up period was 8.1 (7.9 - 9.8) years. The patients were 73.5 years old (46 - 91) at the time of the revision surgery. One case had a septic course necessitating revision surgery. The other cases showed increasing homogeneity compared to the opposite side and gradual adaptation to the radiological structures found there beforehand. Screw breakage was observed in 3 cases but no implant failure, migration tendency or change in the position of the reconstruction ring or PE-cup.
Conclusion: Despite the low case numbers and different baseline situations, it can be concluded that thermodisinfected cancellous bone chips enable similarly good acetabular reconstruction as the routinely tried and tested cryoconserved, non-processed bone bank allograft, which is becoming increasingly difficult to obtain because of altered guidelines and legislation. The newly developed reconstruction ring has proven itself because of the improved range of sizes and the possibility of adjustment to the anatomical circumstances together with its outstanding material characteristics in clinical use.
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http://dx.doi.org/10.1055/s-2007-965660 | DOI Listing |
Am J Sports Med
January 2025
Midwest Orthopaedics at Rush University Medical Center, Chicago, Illinois, USA.
Background: Mismatch between osteochondral allograft (OCA) donor and recipient sex has been shown to negatively affect outcomes. This study accounts for additional donor variables and clinically relevant outcomes.
Purpose: To evaluate whether donor sex, age, donor-recipient sex mismatch, and duration of graft storage affect clinical outcomes and failure rates after knee OCA transplantation.
Am J Sports Med
January 2025
Department of Orthopaedic Surgery, Washington University School of Medicine, St. Louis, Missouri, USA.
Background: Knee injuries resulting in purely cartilaginous defects are rare, and controversy remains regarding the reliability of chondral-only fixation.
Purpose: To systematically review the literature for fixation methods and outcomes after primary fixation of chondral-only defects within the knee.
Study Design: Systematic review; Level of evidence, 5.
Am J Sports Med
January 2025
Department of Orthopaedic Surgery, Samsung Medical Center, School of Medicine, Sungkyunkwan University, Seoul, South Korea.
Background: Studies are still limited on the isolated effect of retear after arthroscopic rotator cuff repair (ARCR) on functional outcomes after the midterm period.
Purpose: To assess the effect of retear at midterm follow-up after ARCR and to identify factors associated with the need for revision surgery.
Study Design: Cohort study; Level of evidence, 3.
Clin J Gastroenterol
January 2025
University of Connecticut, Connecticut, USA.
Marginal ulcers are a common complication following Roux-en-Y bypass surgeries with an approximate incidence of 4.6%. The pathophysiology is complex and risk factors include smoking, nonsteroidal anti-inflammatory drugs (NSAIDs) use, Helicobacter pylori infection, and a larger pouch size.
View Article and Find Full Text PDFJ Cardiothorac Surg
January 2025
Department of Anesthesiology, Fuwai Hospital, National Center for Cardiovascular Diseases, Peking Union Medical College and Chinese Academy of Medical Sciences, No. 167, Beilishi Road, Xicheng District, China.
Background: Heparin, an anticoagulant used in cardiac surgery, can result in heparin rebound (HR), where it returns postoperatively despite being neutralized with protamine. This study was designed to investigate the prevalence of HR in patients undergoing off-pump coronary artery bypass grafting (OPCAB) and evaluate the impact of HR on their short-term outcomes.
Methods: HR was defined by a 10% increase in activated coagulation time (ACT) following two hours of heparin neutralization with protamine, bleeding over 200 mL/h, and abnormal laboratory coagulation examination results.
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