Differential activities of newer antifungal agents against Candida albicans and Candida parapsilosis biofilms.

Aspasia Katragkou Athanasios Chatzimoschou Maria Simitsopoulou Maria Dalakiouridou Eudoxia Diza-Mataftsi Chaido Tsantali Emmanuel Roilides

Antimicrob Agents Chemother

Laboratory of Infectious Diseases, Third Department of Pediatrics, Aristotle University, Hippokration Hospital, 54642 Thessaloniki, Greece.

Published: January 2008

The activities of voriconazole, posaconazole, caspofungin, and anidulafungin against Candida albicans and Candida parapsilosis biofilms were evaluated. In contrast to planktonic cells, the MICs for voriconazole and posaconazole for the biofilms of the two species were high (>or=256 and >64 mg/liter, respectively) but relatively low for the echinocandins caspofungin and anidulafungin (

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2223899	PMC
http://dx.doi.org/10.1128/AAC.00856-07	DOI Listing

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