We report on a woman who gave birth consecutively to an infant with limb body wall complex (LBWC) and then to an infant with amniotic band sequence (ABS). This paper reviews the different etiological hypotheses and the classification problems for the amniotic band diseases. No maternal factors were found, but this clinical report suggests further research in this direction, as well as the need to look more closely at the relation between LBWC and ABS.
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http://dx.doi.org/10.1002/ajmg.a.32018 | DOI Listing |
Children (Basel)
December 2024
German Center for Fetal Surgery & Minimally Invasive Therapy (DZFT), Theodor-Kutzer-Ufer 1-3, 68167 Mannheim, Germany.
Unlabelled: Amniotic band syndrome is a constrictive phenomenon in fetal development that can provoke limb autoamputation, malformation, trunk division, and umbilical cord strangulation. The latter two complications will ultimately lead to fetal demise if left untreated. If detected early enough, select cases may benefit from prenatal resection of the amniotic bands, thus preventing amputation and fetal death.
View Article and Find Full Text PDFCase Rep Obstet Gynecol
December 2024
Department of Obstetrics and Gynecology, Jimma University School of Medicine, Jimma, Ethiopia.
Fetal limb anomaly presentation varies greatly. It can present as amelia (complete absence of skeletal part of one or more limb), meromelia (partial absence of skeletal part of one or more limb), phocomelia (only rudimentary limb formed), and minor limb disorders like polydactyly. The complete absence of the four fetal limbs is extremely rare.
View Article and Find Full Text PDFPaediatr Perinat Epidemiol
December 2024
Department of Epidemiology, Boston University School of Public Health, Boston, Massachusetts, USA.
Background: Empirically evaluating the potential impact of recall bias on observed associations of prenatal medication exposure is crucial.
Objective: We sought to assess the effects of exposure misclassification on previous studies of the use of nonsteroidal anti-inflammatory drugs (NSAIDs) in early pregnancy and increased risk of amniotic band syndrome (ABS).
Methods: Using data from the National Birth Defects Prevention Study (NBDPS) on births from 1997 to 2011, we included 189 mothers of infants with ABS and 11,829 mothers of infants without congenital anomalies.
J Hand Surg Asian Pac Vol
December 2024
Department of Plastic, Hand and Reconstructive Microsurgery, Ganga Medical Centre & Hospitals Pvt. Ltd., Coimbatore, Tamil Nadu, India.
Surgical management of constriction ring syndrome (CRS) is individualised due to the heterogenic presentation of the condition. CRS includes constriction rings, acrosyndactyly, nubbins and short digits. Involvement of more than one limb is common and children often need multiple surgeries.
View Article and Find Full Text PDFBioengineering (Basel)
September 2024
Postgraduate Program in Biomedical Engineering, Biomedical Engineering Institute, Universidade Anhembi Morumbi (UAM), São José dos Campos 12247-004, São Paulo, Brazil.
The aim of this study was to evaluate whether a system involving ozonated water and ultrasound causes de-epithelization of the human amniotic membrane (HAM). The experiment protocol was carried out in four stages. Stage I was carried out to determine the duration of the experiment.
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