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Background: Dementia is a life-changing condition for patients and caregivers. Response to a diagnosis often includes grief, shock, and despair. Unfortunately, evidence demonstrates inadequate use of person-centered communication practices during diagnostic disclosure, which adds to psychological distress.
View Article and Find Full Text PDFDementia Care Research and Psychosocial Factors.
Alzheimers Dement
December 2024
College of Medicine, University of Ibadan, Ibadan, Oyo, Nigeria.
Background: The emergence of dementia as a global health challenge necessitates an exploration of its unique epidemiological patterns and risk factors in Sub-Saharan Africa (SSA). Amid a growing elderly population, SSA presents an intriguing paradox of lower-than-expected dementia prevalence, prompting a comprehensive review of epidemiological nuances, lifestyle risk factors, cultural influences, and protective factors. This study critically assessed the current state of dementia research in SSA, aiming to inform tailored interventions and policies.
View Article and Find Full Text PDFImpact of Subarachnoid Hemorrhage on Human Glymphatic Function: A Time-Evolution Magnetic Resonance Imaging Study.
Stroke
January 2025
Department of Neurosurgery, Oslo University Hospital-Rikshospitalet, Norway (P.K.E., A.L., P.A.R., A.G.S., L.M.V.).
Background: Subarachnoid hemorrhage (SAH) is associated with significant mortality and morbidity. The impact of SAH on human glymphatic function remains unknown.
Methods: This prospective, controlled study investigated whether human glymphatic function is altered after SAH, how it differs over time, and possible underlying mechanisms.
Exploring the association between familial hemiplegic migraine genes (, and ) with migraine and epilepsy: A UK Biobank exome-wide association study.
Cephalalgia
January 2025
Department of Biomedicine, Health Aarhus University, Aarhus, Denmark.
Background: Familial hemiplegic migraine (FHM) types 1-3 are associated with protein-altering genetic variants in , and , respectively. These genes have also been linked to epilepsy. Previous studies primarily focused on phenotypes, examining genetic variants in individuals with characteristic FHM symptoms.
View Article and Find Full Text PDFAntibiotic prescribing for care-home residents: a population-based, cross-classified multilevel analysis in Scotland, UK.
Age Ageing
January 2025
School of Medicine, University of Dundee, Dundee, UK.
Background: There is wide variation in antibiotic prescribing across care-homes for older people, with implications for resident outcomes and antimicrobial resistance.
Objective: To quantify variation in antibiotic prescribing and associations with resident, care-home and general practice characteristics.
Design: Population-based analyses using administrative data.
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