Double crush syndrome: an analysis of age, gender and body mass index.

Clin Neurol Neurosurg

Neurology Department, Zahedan University School of Medicine, Khatam Teaching Hospital, Zahedan, Iran.

Published: January 2008

AI Article Synopsis

  • The study evaluates age, gender, BMI, wrist ratio, and nerve conduction velocity as risk factors for double crush syndrome (DCS) among patients with carpal tunnel syndrome (CTS).
  • It involved 142 patients (mostly female) and 109 controls, using clinical measures and nerve conduction studies to compare risk factors.
  • Results indicate that older age and male gender are significant independent risk factors for DCS, highlighting the need for electrophysiologic screening in elderly men with CTS to differentiate it from DCS.

Article Abstract

Objectives: The aim of this study is to evaluate the role of age, gender, body mass index (BMI), wrist ratio and median sensory nerve conduction velocity as independent risk factors for double crush syndrome (DCS) and to analyze the strength of association of these factors.

Patients And Methods: We have undertaken a case-control study in 142 patients (125 females) with carpal tunnel syndrome (CTS) and 109 controls. Based on clinical and electrophysiologic criteria 106 pure CTS patients and 36 DCS patients as well as 62 female and 47 male control subjects were selected from patients and their relatives referred to our tertiary referral hospital. Totally nerve conduction studies and electromyographic examination were done in 201 hands. Height, weight, BMI, wrist width, depth, circumference and ratio were measured in all patients and control group. Mean values of different risk factors for DCS group and controls were measured. A logistic regression analysis was conducted to evaluate odds ratio of different risk factors.

Results: The mean values for age was greater in DCS patients than CTS group. Male gender and increasing age had odds ratio of 4.19 (CI 95%: 1.35-12.96) and 1.13 (CI 95%: 1.07-1.19), respectively.

Conclusion: Our study confirms that male gender and increased age are independent risk factors for DCS. We suggest that in elderly men presenting with CTS, electrophysiologic screening for cervical radiculopathy should be considered because the treatment of DCS differs from pure CTS.

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Source
http://dx.doi.org/10.1016/j.clineuro.2007.08.013DOI Listing

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