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Postoperative high-dose-rate brachytherapy alone in stage T1-3N0M0 oral cancer with negative prognostic factors: A retrospective study.
Brachytherapy
December 2024
Department of Oncology and Radiotherapy, University Hospital and Medical Faculty Hradec Kralove Hradec Kralove, Czech Republic.
Purpose: To evaluate treatment outcomes and toxicity in patients with stage T1-3N0M0 oral cancer treated with surgery followed by high-dose-rate brachytherapy (HDR-BT).
Methods And Materials: Retrospective study of 50 patients with stage T1-T3N0 tongue and floor-of-mouth cancer who underwent tumour excision (+ elective neck dissection) followed by postoperative HDR-BT due to the presence of negative prognostic factors (close or positive resection margins, lymphovascular and/or perineural invasion, deep invasion). The plastic tube technique (dose: 18 x 3 Gy b.
Lingual Necrosis in the Setting of Giant Cell Arteritis.
Cureus
November 2024
Department of Internal Medicine, Northeast Georgia Medical Center Gainesville, Gainesville, USA.
Giant cell arteritis (GCA) is a medium-to-large vessel vasculitis most commonly affecting the aortic arch and carotid branches. Lingual necrosis is a rare complication of GCA caused by lingual artery vasculitis due to ischemia. A delay in diagnosis can result in irreversible complications such as tongue amputation.
View Article and Find Full Text PDFProtective effects of quercetin against tongue injury and oxidative stress triggered by irinotecan: a histopathological, biochemical and molecular study.
Toxicol Res (Camb)
December 2024
Department of Anatomy and Embryology, Faculty of Medicine, Benha University, Al Nadi Al Ryadi, Qism Benha, Al-Qalyubia Governorate, Benha 13518, Benha, Egypt.
Introduction: About 80% of patients receiving chemotherapeutics suffer from side effects related to the gastrointestinal tract. Irinotecan (CPT-11) is a chemotherapeutic agent usually used in treating solid tumors. Quercetin (QRT), a bioflavonoid, is an antioxidant and scavenger reactive oxygen species scavenger.
View Article and Find Full Text PDFMandibular tongue-shaped flap reconstruction for lip defects following lip tumor surgery.
J Craniomaxillofac Surg
December 2024
Department of Dermatology, Second Hospital of Jilin University, Changchun, China. Electronic address:
Lip defects due to lip tumor surgery need proper reconstruction to preserve their function. Traditional methods offer various options for lip repair, but each has limitations, and can lead to deformity, asymmetry, or functional impairment. This study aimed to investigate the clinical application of mandibular tongue-shaped flap reconstruction for postoperative defects following lip tumor surgery.
View Article and Find Full Text PDFComment on "Extensive necrosis of the tongue as a very early adverse event of head and neck radiotherapy".
Oral Oncol
December 2024
Department of Oral Surgery and Oral Pathology, School of Dentistry, Federal University of Minas Gerais (UFMG), Belo Horizonte, MG, Brazil.
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