AI Article Synopsis

  • The use of antibiotics in surgical settings is evaluated based on common pathogens from the genital tract and their sensitivity to these drugs.
  • The advantages of prophylactic antibiotics need to be weighed against potential harms, with a focus on minimizing the duration of use to reduce the risk of antibiotic resistance.
  • A single dose of antibiotics, particularly cephalosporins, is recommended for effective prophylaxis.

Article Abstract

The usage of antibiotics for prevention of infection in surgical practice is taken into consideration with the most frequent pathogenic agents, which are isolated from the genital tract and their sensitivity to antibiotics, pharmacokinetic properties of the antibiotic-tissue penetration, duration of action, concentration (without any risk) and established clinical efficiency. The potential benefit from prophylactic antibiotic should always be balanced against the possible damage. The duration of prophylaxis should be as short as it could be, in order to avoid the danger for occurrence of resistant strains. A single antibiotic dose is ideal. Cephalosporins are the most suitable for current prophylaxis.

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