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Branching, capping, and severing in dynamic actin structures. | LitMetric

Branching, capping, and severing in dynamic actin structures.

Phys Rev Lett

School of Natural Sciences, University of California, Merced, California 95344, USA.

Published: August 2007

AI Article Synopsis

Article Abstract

Branched actin networks at the leading edge of a crawling cell evolve via protein-regulated processes such as polymerization, depolymerization, capping, branching, and severing. A formulation of these processes is presented and analyzed to study steady-state network morphology. In bulk, we identify several scaling regimes in severing and branching protein concentrations and find that the coupling between severing and branching is optimally exploited for conditions in vivo. Near the leading edge, we find qualitative agreement with the in vivo morphology.

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Source
http://dx.doi.org/10.1103/PhysRevLett.99.058103DOI Listing

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