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Article Synopsis
  • A 72-year-old man went to the hospital because he had been bleeding in his stool for two weeks.
  • Doctors found out he had a problem with his stomach and a connection to his spleen, which was likely caused by a return of his cancer called Non-Hodgkin's Lymphoma.
  • After getting better in the hospital and not wanting more chemotherapy, he went home and is now getting help from a Palliative Care team.
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Article Synopsis
  • - Gastrosplenic fistula is a rare and serious condition often caused by lymphoma, which can develop spontaneously or post-chemotherapy, and is commonly mistaken for a splenic abscess.
  • - Accurate diagnosis relies on identifying the fistulous tract through computed tomography, and treatment options typically include surgical resection and chemotherapy.
  • - In a case study, two patients with diffuse large B cell lymphoma experienced lethal outcomes, highlighting the poor prognosis of gastrosplenic fistula even after surgical intervention.
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Splenic abscess with spontaneous gastrosplenic fistula: case report and review of the literature.

J Surg Case Rep

December 2023

Fondazione Policlinico Universitario Agostino Gemelli, Catholic University, Largo Francesco Vito 1, 00168 Rome, Italy.

Gastrosplenic fistula (GSF) is an unusual event that might occur in patients with various gastric or splenic diseases. While GSF related to gastric and splenic malignancies is well-documented in the literature, cases of GSF due to a splenic abscess are extremely rare. We experienced the case of a 49-year-old man with a medical history of tricuspid cardiac valve replacement for infective endocarditis who presented with a sudden onset of anemia and melena.

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Gastrosplenic fistula is an uncommon manifestation of malignancy of the stomach and spleen. The aim of this study is to present our 10-year experience on gastrosplenic fistula secondary to malignant etiology. Endoscopy, imaging, and histopathology records of all the patients with gastric and splenic malignant pathologies were reviewed retrospectively.

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Gastrosplenic fistula is a rare complication arising mainly secondary to involvement of the stomach or spleen by lymphoma. A delayed diagnosis is associated with high morbidity and mortality. We present a case of gastrosplenic fistula secondary to gastric and splenic involvement by diffuse large B-cell lymphoma with relevant imaging findings.

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