Parvovirus is the most common viral cause of diarrhea in young puppies. Based on the analysis of a partial VP2 sequence of 54 samples, canine parvovirus type 2c (CPV-2c) (n = 26), CPV-2b (n = 25), and CPV-2 (n = 3) were detected in the United States. The American CPV-2b isolates have unique codons (494 and 572) in VP2.
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http://dx.doi.org/10.1128/JCM.01300-07 | DOI Listing |
BMC Vet Res
December 2024
School of Statistics and Planning, Makerere University, Kampala, Uganda.
Background: In developing countries such as Uganda, domestic dogs suffer high burdens of infectious diseases often with high mortalities. Surveillance data on the common diseases and associated mortalities is however scanty. We thus, present results of a retrospective study of common clinical conditions and mortalities of dogs brought for treatment at the small animal clinic, Makerere University, Kampala, Uganda.
View Article and Find Full Text PDFBMC Biotechnol
December 2024
Biomedical Department, R&D Center, Nitta Gelatin Inc, 2-22, Futamata, Yao City, Osaka, 581-0024, Japan.
Virus Genes
December 2024
College of Veterinary Medicine, Qingdao Agricultural University, Qingdao, 266109, People's Republic of China.
Vet World
October 2024
Facultad de Ciencias de la Salud, Carrera de Medicina Veterinaria, Universidad de Las Américas (UDLA), Quito, Ecuador, Antigua Vía a Nayón S/N, Quito EC 170124, Ecuador.
Background And Aim: Viral gastroenteritis in canines is primarily caused by the canine parvovirus 2 (CPV-2). Infections by this virus can cause severe consequences in dogs, such as fever, vomiting, diarrhea, septicemia, systemic inflammation, and immunosuppression. Therefore, the mortality rate of persistent infections caused by this virus is significantly high.
View Article and Find Full Text PDFJ Virol
November 2024
Guangdong Technological Engineering Research Center for Pets, College of Veterinary Medicine, South China Agricultural University, Guangzhou, Guangdong, China.
Unlabelled: Canine parvovirus type 2 (CPV-2) is a member of the Parvoviridae family, characterized by its small, non-enveloped virions containing a linear single-stranded DNA genome of approximately 5 kb. Parvoviruses entirely reliant on the host cell's division machinery for replication. In this study, we demonstrate that CPV-2 infection triggers the host translation shutoff, a process in which the nonstructural protein 1 (NS1) plays a pivotal role.
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