AI Article Synopsis
- Three cases of viral infections post-lung transplantation were reported, each involving different patients and viruses.
- Case 1 involved a 52-year-old male who developed Epstein-Barr virus viremia and post-transplant lymphoproliferative disorder, treated successfully with rituximab and currently has no recurrence.
- Case 2 involved a 38-year-old male who also developed post-transplant lymphoproliferative disorder after double lung transplantation, treated successfully with rituximab and remains free of recurrence.
- Case 3 involved a 24-year-old woman who experienced ganciclovir-resistant cytomegalovirus viremia after lung transplantation, treated successfully with foscarnet, and
Article Abstract
We experienced 3 cases of viral infections after lung transplantation. Case 1: Fifty-two-year-old male with pulmonary emphysema underwent left single lung transplantation from a cadaveric donor. Three months after transplantation he presented Epstein-Barr virus (EBV) viremia, resulting in multiple lymphadenopathy. Biopsy showed post-transplant lymphproliferative disorder, and he was treated successfully with rituximab. He is well without recurrence around 1 and a half years after treatment. Case 2: Thitry-eight-year-old male with pulmonary emphysema underwent double lung transplantation from a cadaveric donor. Four months after transplantation he showed multiple nodules in both lungs. Percutaneous biopsy showed post-transplant lymphproliferative disorder, and he was treated successfully with rituximab. He is well without recurrence more than 2 years after treatment. Case 3 : Twenty-four-year-old woman with lymphangioleiomyomatosis underwent living-related bilateral lobar lung transplantation. Three months after lung transplantation she presented cytomegalovirus viremia. Since it proved to be ganciclovir-resistant cytomegalovirus infection, she was treated with foscarnet successfully. She is well without recurrence about 2 and a half years after treatment.
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