The data available in the literature and the authors' observation of hepatic adenoma polycysticum developed in a 34-year-old female are given. A comprehensive morphological (histological and immunohistochemical) study has shown that the cystic wall is lined with the cylindrical epithelium that has a positive reaction with cytokeratins 7, 18, 19, and 20, CA 19-9. The underlining tissue resembles ovarian tissue and positively reacts with vimentin, estrogen, and progesterone.
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